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Cellosaurus KH88 B4D6 (CVCL_V005)

[Text version]
Cell line name KH88 B4D6
Synonyms KH88-B4D6; KH88 subclone B4D6; KH88B4D6; B4D6
Accession CVCL_V005
Resource Identification Initiative To cite this cell line use: KH88 B4D6 (RRID:CVCL_V005)
Comments Population: Japanese.
Doubling time: 20-26 hours (PubMed=8289484).
Microsatellite instability: Stable (MSS) (PubMed=10739008; PubMed=11226526).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (PubMed=10071072; PubMed=10576511).
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_G364 (KH88)
Sex of cell Male
Age at sampling 69Y
Category Cancer cell line
Publications

PubMed=8289484
Tatsuo Furukawa, Tadashi Koike, Wang Ying, Kenji Kishi, Sadao Aoki, Takao Gotoh, Shigeo Hashimoto, Hiroyuki Saitoh, Masaharu Hanano, Shoji Shinada, Yoshiaki Moriyama ...Show all 17 authors... , Masuhiro Takahashi, Yoshiyasu Endo, Hiromitsu Okano, Taira Maekawa, Tatsuo Abe, Akira Shibata; Show fewer authors
Establishment of a new cell line with the characteristics of a multipotential progenitor from a patient with chronic myelogenous leukemia in early erythroblastic crisis.
Leukemia 8:171-180(1994)

PubMed=9644295; DOI=10.1159/000040837
Hiroto Kaneko, Shigeo Horiike, Yuri Sasai, Toshiki Iwai, Makoto Nakao, Shouhei Yokota, Masafumi Taniwaki, Kei Kashima, Shin-ichi Misawa;
Rare alteration of genomic structure or expression of the DPC4 gene in myelogenous leukemias.
Acta Haematol. 99:187-190(1998)

PubMed=10071072; DOI=10.1016/S0145-2126(98)00171-4
Hans Gunther Drexler, Roderick A.F. MacLeod, Cord C. Uphoff;
Leukemia cell lines: in vitro models for the study of Philadelphia chromosome-positive leukemia.
Leuk. Res. 23:207-215(1999)

PubMed=10576511; DOI=10.1016/S0145-2126(99)00131-9
Cord C. Uphoff, Silke Habig, Severine Fombonne, Yoshinobu Matsuo, Hans Gunther Drexler;
ABL-BCR expression in BCR-ABL-positive human leukemia cell lines.
Leuk. Res. 23:1055-1060(1999)

PubMed=10739008; DOI=10.1016/S0145-2126(99)00182-4
Kaoru Inoue, Takashi Kohno, Satoshi Takakura, Yasuhide Hayashi, Hideaki Mizoguchi, Jun Yokota;
Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines.
Leuk. Res. 24:255-262(2000)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=11226526; DOI=10.1016/S0145-2126(00)00121-1
Kaoru Inoue, Takashi Kohno, Satoshi Takakura, Yasuhide Hayashi, Hideaki Mizoguchi, Jun Yokota;
Corrigendum to: Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines Leukemia Research 24 (2000), 255-262.
Leuk. Res. 25:275-278(2001)

PubMed=14603991; DOI=10.1081/IMM-120025102
Flavio Monteiro Ayres, Miwako Narita, Masuhiro Takahashi, Louie Alldawi, Ai-Chun Liu, Yasser Osman, Takashi Abe, Toshio Yano, Minori Sakaue, Ken Toba, Tatsuo Furukawa, Yoshifusa Aizawa;
A comparative study of the JAM test and 51Cr-release assay to assess the cytotoxicity of dendritic cells on hematopoietic tumor cells.
Immunol. Invest. 32:219-227(2003)

Cross-references
Encyclopedic resources Wikidata; Q54899864
Polymorphism and mutation databases Cosmic; 949097
Entry history
Entry creation16-Apr-2014
Last entry update19-Dec-2024
Version number13