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Cellosaurus HuCL-22 (CVCL_UZ26)

[Text version]
Cell line name HuCL-22
Accession CVCL_UZ26
Resource Identification Initiative To cite this cell line use: HuCL-22 (RRID:CVCL_UZ26)
Comments Senescence: Senesces at 24 PDL (PubMed=12077343).
Derived from site: In situ; Eye, cornea, limbus; UBERON=UBERON_0006761.
Cell type: Keratinocyte; CL=CL_0000312.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_UZ28 (HCLE)
Sex of cell Male
Age at sampling 30Y
Category Finite cell line
Web pages Provider; BWH dermatology; -; https://dermatology.bwh.harvard.edu/docs/Cell-Culture-Core-Cell-Lines.pdf
Publications

PubMed=12077343; DOI=10.1128/mcb.22.14.5157-5172.2002; PMCID=PMC139780
Rheinwald J.G., Hahn W.C., Ramsey M.R., Wu J.Y., Guo Z.-Y., Tsao H., De Luca M., Catricala C., O'Toole K.M.
A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status.
Mol. Cell. Biol. 22:5157-5172(2002)

Cross-references
Encyclopedic resources Wikidata; Q94307299
Entry history
Entry creation25-Feb-2019
Last entry update10-Apr-2025
Version number8