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Cellosaurus AHH-1 TK+/- (CVCL_UU61)

[Text version]
Cell line name AHH-1 TK+/-
Synonyms AHH-1 tk+/-
Accession CVCL_UU61
Resource Identification Initiative To cite this cell line use: AHH-1 TK+/- (RRID:CVCL_UU61)
Comments Population: Caucasian.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg282Trp (c.844C>T); ClinVar=VCV000012364; Zygosity=Unspecified (PubMed=8841477).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3640 (AHH-1)
Children:
CVCL_UU62 (AHH-1 TK+/- L3)CVCL_C7JT (h1B1/OR)
Sex of cell Male
Age at sampling 33Y
Category Transformed cell line
Publications

PubMed=2307151; DOI=10.1002/em.2850150203
Crespi C.L., Seixas G.M., Turner T., Penman B.W.
Sodium fluoride is a less efficient human cell mutagen at low concentrations.
Environ. Mol. Mutagen. 15:71-77(1990)

PubMed=7739402; DOI=10.1093/mutage/10.1.53
Dobo K.L., Giver C.R., Eastmond D.A., Rumbos H.S., Grosovsky A.J.
Extensive loss of heterozygosity accounts for differential mutation rate on chromosome 17q in human lymphoblasts.
Mutagenesis 10:53-58(1995)

PubMed=8841477; DOI=10.1016/0027-5107(96)00133-9
Morris S.M., Manjanatha M.G., Shelton S.D., Domon O.E., McGarrity L.J., Casciano D.A.
A mutation in the p53 tumor suppressor gene of AHH-1 tk+/- human lymphoblastoid cells.
Mutat. Res. 356:129-134(1996)

Cross-references
Encyclopedic resources Wikidata; Q93323819
Polymorphism and mutation databases IARC_TP53; 7283
Entry history
Entry creation25-Feb-2019
Last entry update29-Jun-2023
Version number6