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Cellosaurus imHC (CVCL_UR52)

[Text version]
Cell line name imHC
Synonyms BMI/hTERT-MSC; immortalized Hepatocyte-like Cell line
Accession CVCL_UR52
Resource Identification Initiative To cite this cell line use: imHC (RRID:CVCL_UR52)
Comments Group: Malaria research cell line.
Characteristics: Supports Plasmodium vivax liver-stage development (PubMed=29370800).
Transfected with: HGNC; 11730; TERT.
Transfected with: MGI; MGI:88174; Bmi1.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: Mesenchymal stem cell derived hepatocyte.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Telomerase immortalized cell line

PubMed=21961524; DOI=10.1186/1472-6750-11-89
Sa-ngiamsuntorn K., Wongkajornsilp A., Kasetsinsombat K., Duangsa-ard S., Nuntakarn L., Borwornpinyo S., Akarasereenont P., Limsrichamrern S., Hongeng S.
Upregulation of CYP 450s expression of immortalized hepatocyte-like cells derived from mesenchymal stem cells by enzyme inducers.
BMC Biotechnol. 11:89.1-89.15(2011)

PubMed=29370800; DOI=10.1186/s12936-018-2198-4
Pewkliang Y., Rungin S., Lerdpanyangam K., Duangmanee A., Kanjanasirirat P., Suthivanich P., Sa-ngiamsuntorn K., Borwornpinyo S., Sattabongkot J., Patrapuvich R., Hongeng S.
A novel immortalized hepatocyte-like cell line (imHC) supports in vitro liver stage development of the human malarial parasite Plasmodium vivax.
Malar. J. 17:50.1-50.14(2018)

PubMed=31381603; DOI=10.1371/journal.pone.0220825
Pongjantarasatian S., Kadegasem P., Sasanakul W., Sa-ngiamsuntorn K., Borwornpinyo S., Sirachainan N., Chuansumrit A., Tanratana P., Hongeng S.
Coagulant activity of recombinant human factor VII produced by lentiviral human F7 gene transfer in immortalized hepatocyte-like cell line.
PLoS ONE 14:E0220825-E0220825(2019)

Encyclopedic resources Wikidata; Q94316264
Entry history
Entry creation25-Feb-2019
Last entry update30-Jan-2024
Version number7