Cellosaurus cell line 585B1-868 (CVCL

Cellosaurus 585B1-868 (CVCL_UP50)

Cross-references
Cell line name	585B1-868
Synonyms	BTAG 585B1-868; 585B1 BTAG (XY)
Accession	CVCL_UP50
Resource Identification Initiative	To cite this cell line use: 585B1-868 (RRID:CVCL_UP50)
Comments	From: Center for iPS Cell Research and Application, Kyoto University; Kyoto; Japan. Population: Japanese. Characteristics: Using TALEN a 2A-tdTomato construct was inserted at the C-terminal end of PRDM1 (BLIMP1) as well as 2A-EGFP construct at the C-terminal end of TFAP2C. Genetic integration: Method=TALEN; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP). Genetic integration: Method=TALEN; Gene=FPbase; PGG5S; tdTomato (Note=Bright red fluorescent protein derived from drFP583 (DsRed)). Omics: Transcriptomics; RNAseq. Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_DQ07 (585B1)
Sex of cell	Male
Age at sampling	30-39Y
Category	Induced pluripotent stem cell
Publications	PubMed=26189426; DOI=10.1016/j.stem.2015.06.014 Kotaro Sasaki, Shihori Yokobayashi, Tomonori Nakamura, Ikuhiro Okamoto, Yukihiro Yabuta, Kazuki Kurimoto, Hiroshi Ohta, Yoshinobu Moritoki, Chizuru Iwatani, Hideaki Tsuchiya, Shinichiro Nakamura ...Show all 21 authors... , Kiyotoshi Sekiguchi, Tetsushi Sakuma, Takashi Yamamoto, Takahide Mori, Knut Woltjen, Masato Nakagawa, Takuya Yamamoto, Kazutoshi Takahashi, Shinya Yamanaka, Mitinori Saitou; Show fewer authors Robust in vitro induction of human germ cell fate from pluripotent stem cells. Cell Stem Cell 17:178-194(2015) PubMed=28453617; DOI=10.1093/biolre/iox038 Shihori Yokobayashi, Keisuke Okita, Masato Nakagawa, Tomonori Nakamura, Yukihiro Yabuta, Takuya Yamamoto, Mitinori Saitou; Clonal variation of human induced pluripotent stem cells for induction into the germ cell fate. Biol. Reprod. 96:1154-1166(2017) PubMed=30237246; DOI=10.1126/science.aat1674 Chika Yamashiro, Kotaro Sasaki, Yukihiro Yabuta, Yoji Kojima, Tomonori Nakamura, Ikuhiro Okamoto, Shihori Yokobayashi, Yusuke Murase, Yukiko Ishikura, Kenjiro Shirane, Hiroyuki Sasaki ...Show all 13 authors... , Takuya Yamamoto, Mitinori Saitou; Show fewer authors Generation of human oogonia from induced pluripotent stem cells in vitro. Science 362:356-360(2018)
Encyclopedic resources	Wikidata; Q93307890
Gene expression databases	GEO; GSM2592205 GEO; GSM2592206
Entry history
Entry creation	25-Feb-2019
Last entry update	10-Apr-2025
Version number	10