ID   585B1-868
AC   CVCL_UP50
SY   BTAG 585B1-868; 585B1 BTAG (XY)
DR   GEO; GSM2592205
DR   GEO; GSM2592206
DR   Wikidata; Q93307890
RX   PubMed=26189426;
RX   PubMed=28453617;
RX   PubMed=30237246;
CC   From: Center for iPS Cell Research and Application, Kyoto University; Kyoto; Japan.
CC   Population: Japanese.
CC   Characteristics: Using TALEN a 2A-tdTomato construct was inserted at the C-terminal end of PRDM1 (BLIMP1) as well as 2A-EGFP construct at the C-terminal end of TFAP2C.
CC   Genetic integration: Method=TALEN; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
CC   Genetic integration: Method=TALEN; Gene=FPbase; PGG5S; tdTomato (Note=Bright red fluorescent protein derived from drFP583 (DsRed)).
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_DQ07 ! 585B1
SX   Male
AG   30-39Y
CA   Induced pluripotent stem cell
DT   Created: 25-02-19; Last updated: 10-04-25; Version: 10
//
RX   PubMed=26189426; DOI=10.1016/j.stem.2015.06.014;
RA   Sasaki K., Yokobayashi S., Nakamura T., Okamoto I., Yabuta Y.,
RA   Kurimoto K., Ohta H., Moritoki Y., Iwatani C., Tsuchiya H.,
RA   Nakamura S., Sekiguchi K., Sakuma T., Yamamoto T., Mori T.,
RA   Woltjen K., Nakagawa M., Yamamoto T., Takahashi K., Yamanaka S.,
RA   Saitou M.;
RT   "Robust in vitro induction of human germ cell fate from pluripotent
RT   stem cells.";
RL   Cell Stem Cell 17:178-194(2015).
//
RX   PubMed=28453617; DOI=10.1093/biolre/iox038;
RA   Yokobayashi S., Okita K., Nakagawa M., Nakamura T., Yabuta Y.,
RA   Yamamoto T., Saitou M.;
RT   "Clonal variation of human induced pluripotent stem cells for
RT   induction into the germ cell fate.";
RL   Biol. Reprod. 96:1154-1166(2017).
//
RX   PubMed=30237246; DOI=10.1126/science.aat1674;
RA   Yamashiro C., Sasaki K., Yabuta Y., Kojima Y., Nakamura T.,
RA   Okamoto I., Yokobayashi S., Murase Y., Ishikura Y., Shirane K.,
RA   Sasaki H., Yamamoto T., Saitou M.;
RT   "Generation of human oogonia from induced pluripotent stem cells in
RT   vitro.";
RL   Science 362:356-360(2018).
//