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Cellosaurus MM253-3D (CVCL_UM65)

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Cell line name MM253-3D
Accession CVCL_UM65
Resource Identification Initiative To cite this cell line use: MM253-3D (RRID:CVCL_UM65)
Comments Selected for resistance to: ChEBI; CHEBI_4305; Dacarbazine (DTIC; (5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide)).
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (from parent cell line).
Disease Amelanotic melanoma (NCIt: C3802)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2604 (MM253)
Sex of cell Male
Age at sampling 46Y
Category Cancer cell line
Publications

PubMed=3756862
Kevin Maynard, Peter G. Parsons;
Cross-sensitivity of methylating agents, hydroxyurea, and methotrexate in human tumor cells of the Mer- phenotype.
Cancer Res. 46:5009-5013(1986)

Cross-references
Cell line databases/resources cancercelllines; CVCL_UM65
Encyclopedic resources Wikidata; Q95990203
Entry history
Entry creation25-Feb-2019
Last entry update19-Dec-2024
Version number8