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Cellosaurus WAe009-A-11 (CVCL_UM37)

[Text version]
Cell line name WAe009-A-11
Synonyms H9-p53(WT/R249S); A94-42; CDMLe010-A-11
Accession CVCL_UM37
Resource Identification Initiative To cite this cell line use: WAe009-A-11 (RRID:CVCL_UM37)
Comments From: Cancer Disease Modeling Laboratory, University of Texas Health Center at Houston; Houston; USA.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple_edited; p.Arg249Ser (c.747G>T); ClinVar=VCV000012352; Zygosity=Heterozygous; Note=By TALEN (PubMed=30640060).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9773 (WA09)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
Publications

PubMed=30640060; DOI=10.1016/j.scr.2018.101360
Huo Z.-J., Tu J., Xu A., Li Y., Wang D.-H., Liu M., Zhou R.-J., Zhu D.-D., Lin Y., Gingold J.A., Yen C.-J., Xiao H.-P., Zhao R.-Y.
Generation of a heterozygous p53 R249S mutant human embryonic stem cell line by TALEN-mediated genome editing.
Stem Cell Res. 34:101360-101360(2019)

Cross-references
Cell line databases/resources hPSCreg; WAe009-A-11
Encyclopedic resources Wikidata; Q98134722
Entry history
Entry creation25-Feb-2019
Last entry update29-Jun-2023
Version number8