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Cellosaurus BT075 (CVCL_UK56)

[Text version]
Cell line name BT075
Synonyms BT75; BT-75
Accession CVCL_UK56
Resource Identification Initiative To cite this cell line use: BT075 (RRID:CVCL_UK56)
Comments Group: Cancer stem cell line.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 74Y
Category Cancer cell line
Publications

PubMed=19544433; DOI=10.1002/stem.98
Kelly J.J.P., Stechishin O.D.M., Chojnacki A., Lun X.-Q., Sun B.-C., Senger D.L., Forsyth P., Auer R.N., Dunn J.F., Cairncross J.G., Parney I.F., Weiss S.
Proliferation of human glioblastoma stem cells occurs independently of exogenous mitogens.
Stem Cells 27:1722-1733(2009)

PubMed=26095605; DOI=10.1016/j.stemcr.2015.05.010
Cusulin C., Chesnelong C., Bose P., Bilenky M., Kopciuk K., Chan J.A.W., Cairncross J.G., Jones S.J.M., Marra M.A., Luchman H.A., Weiss S.
Precursor states of brain tumor initiating cell lines are predictive of survival in xenografts and associated with glioblastoma subtypes.
Stem Cell Reports 5:1-9(2015)

PubMed=26245525; DOI=10.1093/neuonc/nov143
Davis B., Shen Y.-Q., Poon C.C., Luchman H.A., Stechishin O.D.M., Pontifex C.S., Wu W., Kelly J.J.P., Blough M.D.
Comparative genomic and genetic analysis of glioblastoma-derived brain tumor-initiating cells and their parent tumors.
Neuro-oncol. 18:350-360(2016)

PubMed=30153289; DOI=10.1371/journal.pone.0202860
Yuan A.L., Ricks C.B., Bohm A.K., Lun X.-Q., Maxwell L., Safdar S., Bukhari S., Gerber A., Sayeed W., Bering E.A., Pedersen H., Chan J.A.W., Shen Y.-Q., Marra M., Kaplan D.R., Mason W., Goodman L.D., Ezhilarasan R., Kaufmann A.B., Cabral M., Robbins S.M., Senger D.L., Cahill D.P., Sulman E.P., Cairncross J.G., Blough M.D.
ABT-888 restores sensitivity in temozolomide resistant glioma cells and xenografts.
PLoS ONE 13:E0202860-E0202860(2018)

Cross-references
Encyclopedic resources Wikidata; Q93432806
Entry history
Entry creation25-Feb-2019
Last entry update29-Jun-2023
Version number5