ID   BT075
AC   CVCL_UK56
SY   BT75; BT-75
DR   Wikidata; Q93432806
RX   PubMed=19544433;
RX   PubMed=26095605;
RX   PubMed=26245525;
RX   PubMed=30153289;
CC   Group: Cancer stem cell line.
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: In situ; Brain; UBERON=UBERON_0000955.
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   74Y
CA   Cancer cell line
DT   Created: 25-02-19; Last updated: 10-04-25; Version: 6
//
RX   PubMed=19544433; DOI=10.1002/stem.98;
RA   Kelly J.J.P., Stechishin O.D.M., Chojnacki A., Lun X.-Q., Sun B.-C.,
RA   Senger D.L., Forsyth P., Auer R.N., Dunn J.F., Cairncross J.G.,
RA   Parney I.F., Weiss S.;
RT   "Proliferation of human glioblastoma stem cells occurs independently
RT   of exogenous mitogens.";
RL   Stem Cells 27:1722-1733(2009).
//
RX   PubMed=26095605; DOI=10.1016/j.stemcr.2015.05.010; PMCID=PMC4618251;
RA   Cusulin C., Chesnelong C., Bose P., Bilenky M., Kopciuk K., Chan J.A.-W.,
RA   Cairncross J.G., Jones S.J.M., Marra M.A., Luchman H.A., Weiss S.;
RT   "Precursor states of brain tumor initiating cell lines are predictive
RT   of survival in xenografts and associated with glioblastoma
RT   subtypes.";
RL   Stem Cell Reports 5:1-9(2015).
//
RX   PubMed=26245525; DOI=10.1093/neuonc/nov143; PMCID=PMC4767234;
RA   Davis B., Shen Y.-Q., Poon C.C., Luchman H.A., Stechishin O.D.M.,
RA   Pontifex C.S., Wu W., Kelly J.J.P., Blough M.D.;
RG   Terry Fox Research Institute Glioblastoma Consortium;
RT   "Comparative genomic and genetic analysis of glioblastoma-derived
RT   brain tumor-initiating cells and their parent tumors.";
RL   Neuro-oncol. 18:350-360(2016).
//
RX   PubMed=30153289; DOI=10.1371/journal.pone.0202860; PMCID=PMC6112648;
RA   Yuan A.L., Ricks C.B., Bohm A.K., Lun X.-Q., Maxwell L., Safdar S.,
RA   Bukhari S., Gerber A., Sayeed W., Bering E.A., Pedersen H.,
RA   Chan J.A.-W., Shen Y.-Q., Marra M.A., Kaplan D.R., Mason W.P., Goodman L.D.,
RA   Ezhilarasan R., Kaufmann A.B., Cabral M., Robbins S.M., Senger D.L.,
RA   Cahill D.P., Sulman E.P., Cairncross J.G., Blough M.D.;
RT   "ABT-888 restores sensitivity in temozolomide resistant glioma cells
RT   and xenografts.";
RL   PLoS ONE 13:e0202860.1-e0202860.18(2018).
//