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Cellosaurus BT050 (CVCL_UK38)

[Text version]
Cell line name BT050
Synonyms BT50; BT-50
Accession CVCL_UK38
Resource Identification Initiative To cite this cell line use: BT050 (RRID:CVCL_UK38)
Comments Group: Cancer stem cell line.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (PubMed=26095605).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 61Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-3408

Markers:
AmelogeninX,Y
CSF1PO10,11,12
D5S81812
D7S8209,10
D13S31712
D16S53911,12
TH017
TPOX8,11
vWA18

Run an STR similarity search on this cell line
Publications

PubMed=26095605; DOI=10.1016/j.stemcr.2015.05.010
Cusulin C., Chesnelong C., Bose P., Bilenky M., Kopciuk K., Chan J.A.W., Cairncross J.G., Jones S.J.M., Marra M.A., Luchman H.A., Weiss S.
Precursor states of brain tumor initiating cell lines are predictive of survival in xenografts and associated with glioblastoma subtypes.
Stem Cell Reports 5:1-9(2015)

PubMed=27006494; DOI=10.1158/1078-0432.CCR-15-1798
Lun X.-Q., Wells J.C., Grinshtein N., King J.C., Hao X.-G., Dang N.-H., Wang X.-L., Aman A., Uehling D., Datti A., Wrana J.L., Easaw J.C., Luchman H.A., Weiss S., Cairncross J.G., Kaplan D.R., Robbins S.M., Senger D.L.
Disulfiram when combined with copper enhances the therapeutic effects of temozolomide for the treatment of glioblastoma.
Clin. Cancer Res. 22:3860-3875(2016)

Cross-references
Cell line collections (Providers) ATCC; CRL-3408
Encyclopedic resources Wikidata; Q93432779
Entry history
Entry creation25-Feb-2019
Last entry update02-May-2024
Version number8