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Cellosaurus BT050 (CVCL_UK38)

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Cell line name BT050
Synonyms BT50; BT-50
Accession CVCL_UK38
Resource Identification Initiative To cite this cell line use: BT050 (RRID:CVCL_UK38)
Comments Group: Cancer stem cell line.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Sequence variations
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 61Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-3408

Markers:
AmelogeninX,Y
CSF1PO10,11,12
D5S81812
D7S8209,10
D13S31712
D16S53911,12
TH017
TPOX8,11
vWA18

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Publications

PubMed=26095605; DOI=10.1016/j.stemcr.2015.05.010; PMCID=PMC4618251
Carlo Cusulin, Charles Chesnelong, Pinaki Bose, Misha Bilenky, Karen Kopciuk, Jennifer Ai-Wen Chan, J. Gregory Cairncross, Steven J.M. Jones, Marco Antonio Marra, Hema Artee Luchman, Samuel Weiss;
Precursor states of brain tumor initiating cell lines are predictive of survival in xenografts and associated with glioblastoma subtypes.
Stem Cell Reports 5:1-9(2015)

PubMed=27006494; DOI=10.1158/1078-0432.CCR-15-1798
Xue-Qing Lun, J. Connor Wells, Natalie Grinshtein, Jennifer C. King, Xiao-Guang Hao, Ngoc-Ha Dang, Xiu-Ling Wang, Ahmed Aman, David Uehling, Alessandro Datti, Jeffrey L. Wrana ...Show all 18 authors... , Jacob Chirakkattu Easaw, Hema Artee Luchman, Samuel Weiss, J. Gregory Cairncross, David Ross Kaplan, Stephen M. Robbins, Donna L. Senger; Show fewer authors
Disulfiram when combined with copper enhances the therapeutic effects of temozolomide for the treatment of glioblastoma.
Clin. Cancer Res. 22:3860-3875(2016)

Cross-references
Cell line collections (Providers) ATCC; CRL-3408
Encyclopedic resources Wikidata; Q93432779
Entry history
Entry creation25-Feb-2019
Last entry update10-Apr-2025
Version number10