ID   BT050
AC   CVCL_UK38
SY   BT50; BT-50
DR   ATCC; CRL-3408
DR   Wikidata; Q93432779
RX   PubMed=26095605;
RX   PubMed=27006494;
CC   Group: Cancer stem cell line.
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=26095605).
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: In situ; Brain; UBERON=UBERON_0000955.
ST   Source(s): ATCC=CRL-3408
ST   Amelogenin: X,Y
ST   CSF1PO: 10,11,12
ST   D13S317: 12
ST   D16S539: 11,12
ST   D5S818: 12
ST   D7S820: 9,10
ST   TH01: 7
ST   TPOX: 8,11
ST   vWA: 18
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   61Y
CA   Cancer cell line
DT   Created: 25-02-19; Last updated: 10-04-25; Version: 10
//
RX   PubMed=26095605; DOI=10.1016/j.stemcr.2015.05.010; PMCID=PMC4618251;
RA   Cusulin, Carlo
RA   Chesnelong, Charles
RA   Bose, Pinaki
RA   Bilenky, Misha
RA   Kopciuk, Karen
RA   Chan, Jennifer Ai-Wen
RA   Cairncross, J. Gregory
RA   Jones, Steven J.M.
RA   Marra, Marco Antonio
RA   Luchman, Hema Artee
RA   Weiss, Samuel
RT   "Precursor states of brain tumor initiating cell lines are predictive
RT   of survival in xenografts and associated with glioblastoma
RT   subtypes.";
RL   Stem Cell Reports 5:1-9(2015).
//
RX   PubMed=27006494; DOI=10.1158/1078-0432.CCR-15-1798;
RA   Lun, Xue-Qing
RA   Wells, J. Connor
RA   Grinshtein, Natalie
RA   King, Jennifer C.
RA   Hao, Xiao-Guang
RA   Dang, Ngoc-Ha
RA   Wang, Xiu-Ling
RA   Aman, Ahmed
RA   Uehling, David
RA   Datti, Alessandro
RA   Wrana, Jeffrey L.
RA   Easaw, Jacob C.
RA   Luchman, Hema Artee
RA   Weiss, Samuel
RA   Cairncross, J. Gregory
RA   Kaplan, David Ross
RA   Robbins, Stephen M.
RA   Senger, Donna L.
RT   "Disulfiram when combined with copper enhances the therapeutic effects
RT   of temozolomide for the treatment of glioblastoma.";
RL   Clin. Cancer Res. 22:3860-3875(2016).
//