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Cellosaurus NLF-TrkB, clone #6 (CVCL_UJ93)

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Cell line name NLF-TrkB, clone #6
Synonyms NLF-TrkB, NTA#6
Accession CVCL_UJ93
Resource Identification Initiative To cite this cell line use: NLF-TrkB, clone #6 (RRID:CVCL_UJ93)
Comments Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:8032; NTRK2.
Sequence variations
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Arg524Met (c.1571G>T); Zygosity=Heterozygous (from parent cell line).
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_E217 (NLF)
Sex of cell Male
Age at sampling 3Y
Category Cancer cell line
Publications

PubMed=26797418; DOI=10.1016/j.canlet.2016.01.018; PMCID=PMC4792275
Radhika Iyer, Lea Wehrmann, Rebecca L. Golden, Koumudi Naraparaju, Jamie L. Croucher, Suzanne P. MacFarland, Peng Guan, Venkatadri Kolla, Ge Wei, Nicholas Cam, Gang Li ...Show all 13 authors... , Zachary Hornby, Garrett M. Brodeur; Show fewer authors
Entrectinib is a potent inhibitor of Trk-driven neuroblastomas in a xenograft mouse model.
Cancer Lett. 372:179-186(2016)

Cross-references
Cell line collections (Providers) Kerafast; ECP010
Encyclopedic resources Wikidata; Q98127940
Entry history
Entry creation25-Feb-2019
Last entry update19-Dec-2024
Version number8