Cellosaurus cell line NLF-TrkB, clone #6 (CVCL

Cross-references
Cell line name	NLF-TrkB, clone #6
Synonyms	NLF-TrkB, NTA#6
Accession	CVCL_UJ93
Resource Identification Initiative	To cite this cell line use: NLF-TrkB, clone #6 (RRID:CVCL_UJ93)
Comments	Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:8032; NTRK2.
Sequence variations	Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Arg524Met (c.1571G>T); Zygosity=Heterozygous (from parent cell line).
Disease	Neuroblastoma (NCIt: C3270) Neuroblastoma (ORDO: Orphanet_635)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_E217 (NLF)
Sex of cell	Male
Age at sampling	3Y
Category	Cancer cell line
Publications	PubMed=26797418; DOI=10.1016/j.canlet.2016.01.018; PMCID=PMC4792275 Radhika Iyer, Lea Wehrmann, Rebecca L. Golden, Koumudi Naraparaju, Jamie L. Croucher, Suzanne P. MacFarland, Peng Guan, Venkatadri Kolla, Ge Wei, Nicholas Cam, Gang Li ...Show all 13 authors... , Zachary Hornby, Garrett M. Brodeur; Show fewer authors Entrectinib is a potent inhibitor of Trk-driven neuroblastomas in a xenograft mouse model. Cancer Lett. 372:179-186(2016)
Cell line collections (Providers)	Kerafast; ECP010
Encyclopedic resources	Wikidata; Q98127940
Entry history
Entry creation	25-Feb-2019
Last entry update	19-Dec-2024
Version number	8