Cellosaurus logo
expasy logo

Cellosaurus N6-1000 (CVCL_UJ07)

[Text][XML][JSON]
Cell line name N6-1000
Accession CVCL_UJ07
Resource Identification Initiative To cite this cell line use: N6-1000 (RRID:CVCL_UJ07)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_4911; Etoposide (VP-16).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene fusion; HGNC; HGNC:50800; DUX4 + HGNC; HGNC:5477; IGH; Name(s)=IGH-DUX4; Note=The translocation occurs in the silenced IGH allele (from parent cell line).
  • Mutation; HGNC; HGNC:3236; EGFR; Simple; p.Arg1068Ter (c.3202C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Ala146Thr (c.436G>A); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9864; RARA; Simple; p.Gln45Ter (c.133C>T); ClinVar=VCV000393019; Zygosity=Heterozygous (from parent cell line).
Disease Adult B acute lymphoblastic leukemia (NCIt: C9143)
Precursor B-cell acute lymphoblastic leukemia (ORDO: Orphanet_99860)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0092 (NALM-6)
Sex of cell Male
Age at sampling 19Y
Category Cancer cell line
Publications

PubMed=1370437; DOI=10.1002/ijc.2910500223
Robin Strong Treichel, Sarah Olken;
The relationship between multi-drug resistance and resistance to natural-killer-cell and lymphokine-activated killer-cell lysis in human leukemic cell lines.
Int. J. Cancer 50:305-310(1992)

Cross-references
Cell line databases/resources cancercelllines; CVCL_UJ07
Encyclopedic resources Wikidata; Q95991925
Entry history
Entry creation25-Feb-2019
Last entry update19-Dec-2024
Version number12