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Cellosaurus FT237 (CVCL_UH59)

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Cell line name FT237
Synonyms hTERT FT237; hTERT FT 237
Accession CVCL_UH59
Resource Identification Initiative To cite this cell line use: FT237 (RRID:CVCL_UH59)
Comments Doubling time: ~32 hours (ATCC=CRL-3446).
Knockout cell: Method=shRNA knockdown; HGNC; HGNC:11998; TP53.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1773; CDK4 (Note=With p.Arg24Cys).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Fallopian tube; UBERON=UBERON_0003889.
Cell type: Fallopian tube secretory epithelial cell; CL=CL_4030006.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Telomerase immortalized cell line
Publications

PubMed=22936217; DOI=10.1038/nprot.2012.097; PMCID=PMC7433321
Alison M. Karst, Ronny I. Drapkin;
Primary culture and immortalization of human fallopian tube secretory epithelial cells.
Nat. Protoc. 7:1755-1764(2012)

PubMed=26364602; DOI=10.1038/onc.2015.288; PMCID=PMC4791205
Guo-Hua Hua, Xiang-Min Lv, Chun-Bo He, Steven Wesley Remmenga, Kerry Julene Rodabaugh, Ji-Xin Dong, Li-Guo Yang, Subodh Mukund Lele, Pei-Xin Yang, Jin Zhou, Alison M. Karst ...Show all 14 authors... , Ronny I. Drapkin, John S. Davis, Cheng Wang; Show fewer authors
YAP induces high-grade serous carcinoma in fallopian tube secretory epithelial cells.
Oncogene 35:2247-2265(2016)

Cross-references
Cell line collections (Providers) ATCC; CRL-3446
Encyclopedic resources Wikidata; Q93557154
Entry history
Entry creation25-Feb-2019
Last entry update14-Aug-2025
Version number10