ID   FT237
AC   CVCL_UH59
SY   hTERT FT237; hTERT FT 237
DR   ATCC; CRL-3446
DR   Wikidata; Q93557154
RX   PubMed=22936217;
RX   PubMed=26364602;
CC   Doubling time: ~32 hours (ATCC=CRL-3446).
CC   Knockout cell: Method=shRNA knockdown; HGNC; HGNC:11998; TP53.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1773; CDK4 (Note=With p.Arg24Cys).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
CC   Derived from site: In situ; Fallopian tube; UBERON=UBERON_0003889.
CC   Cell type: Fallopian tube secretory epithelial cell; CL=CL_4030006.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Age unspecified
CA   Telomerase immortalized cell line
DT   Created: 25-02-19; Last updated: 14-08-25; Version: 10
//
RX   PubMed=26364602; DOI=10.1038/onc.2015.288; PMCID=PMC4791205;
RA   Hua, Guo-Hua
RA   Lv, Xiang-Min
RA   He, Chun-Bo
RA   Remmenga, Steven Wesley
RA   Rodabaugh, Kerry Julene
RA   Dong, Ji-Xin
RA   Yang, Li-Guo
RA   Lele, Subodh Mukund
RA   Yang, Pei-Xin
RA   Zhou, Jin
RA   Karst, Alison M.
RA   Drapkin, Ronny I.
RA   Davis, John S.
RA   Wang, Cheng
RT   "YAP induces high-grade serous carcinoma in fallopian tube secretory
RT   epithelial cells.";
RL   Oncogene 35:2247-2265(2016).
//
RX   PubMed=22936217; DOI=10.1038/nprot.2012.097; PMCID=PMC7433321;
RA   Karst, Alison M.
RA   Drapkin, Ronny I.
RT   "Primary culture and immortalization of human fallopian tube secretory
RT   epithelial cells.";
RL   Nat. Protoc. 7:1755-1764(2012).
//