Cellosaurus logo
expasy logo

Cellosaurus FT194 (CVCL_UH58)

[Text][XML][JSON]
Cell line name FT194
Synonyms hTERT FT194; hTERT FT 194
Accession CVCL_UH58
Secondary accession CVCL_A4AW
Resource Identification Initiative To cite this cell line use: FT194 (RRID:CVCL_UH58)
Comments Doubling time: ~32 hours (ATCC=CRL-3445).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Fallopian tube; UBERON=UBERON_0003889.
Cell type: Fallopian tube secretory epithelial cell; CL=CL_4030006.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_E3FJ (FT194-MXIV)CVCL_E3FE (FT194-YAP)CVCL_E3FF (FT194-YAP(S127A))
Sex of cell Female
Age at sampling Age unspecified
Category Transformed cell line
STR profile Source(s): ATCC=CRL-3445

Markers:
AmelogeninX
CSF1PO11,13
D5S81811,12
D7S82010,13
D13S31711
D16S53911,12
TH018,9.3
TPOX8
vWA16,17

Run an STR similarity search on this cell line
Publications

PubMed=24332043; DOI=10.1016/j.ccr.2013.10.013; PMCID=PMC3917315
Ruth Perets, Gregory Andrew Wyant, Katherine W. Muto, Jonathan G. Bijron, Barish B. Poole, Kenneth T. Chin, Jin-Yun H. Chen, Anders W. Ohman, Corey D. Stepule, Soongu Kwak, Alison M. Karst ...Show all 16 authors... , Michelle S. Hirsch, Sunita R. Setlur, Christopher P. Crum, Daniela M. Dinulescu, Ronny I. Drapkin; Show fewer authors
Transformation of the fallopian tube secretory epithelium leads to high-grade serous ovarian cancer in Brca;Tp53;Pten models.
Cancer Cell 24:751-765(2013)

PubMed=26364602; DOI=10.1038/onc.2015.288; PMCID=PMC4791205
Guo-Hua Hua, Xiang-Min Lv, Chun-Bo He, Steven Wesley Remmenga, Kerry Julene Rodabaugh, Ji-Xin Dong, Li-Guo Yang, Subodh Mukund Lele, Pei-Xin Yang, Jin Zhou, Alison M. Karst ...Show all 14 authors... , Ronny I. Drapkin, John S. Davis, Cheng Wang; Show fewer authors
YAP induces high-grade serous carcinoma in fallopian tube secretory epithelial cells.
Oncogene 35:2247-2265(2016)

Cross-references
Cell line collections (Providers) ATCC; CRL-3445
Encyclopedic resources Wikidata; Q93557134
Entry history
Entry creation25-Feb-2019
Last entry update14-Aug-2025
Version number8