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Cellosaurus FT194-MXIV (CVCL_E3FJ)

[Text version]
Cell line name FT194-MXIV
Accession CVCL_E3FJ
Resource Identification Initiative To cite this cell line use: FT194-MXIV (RRID:CVCL_E3FJ)
Comments Characteristics: Control cell line for FT194-YAP (Cellosaurus=CVCL_E3FE) and FT194-YAP(S127A) (Cellosaurus=CVCL_E3FF) (PubMed=26364602).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:16262; YAP1.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Fallopian tube; UBERON=UBERON_0003889.
Cell type: Fallopian tube secretory epithelial cell; CL=CL_4030006.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_UH58 (FT194)
Sex of cell Female
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=26364602; DOI=10.1038/onc.2015.288; PMCID=PMC4791205
Guo-Hua Hua, Xiang-Min Lv, Chun-Bo He, Steven Wesley Remmenga, Kerry Julene Rodabaugh, Ji-Xin Dong, Li-Guo Yang, Subodh Mukund Lele, Pei-Xin Yang, Jin Zhou, Alison M. Karst ...Show all 14 authors... , Ronny I. Drapkin, John S. Davis, Cheng Wang; Show fewer authors
YAP induces high-grade serous carcinoma in fallopian tube secretory epithelial cells.
Oncogene 35:2247-2265(2016)

Entry history
Entry creation19-Dec-2024
Last entry update14-Aug-2025
Version number2