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Cellosaurus FT190 (CVCL_UH57)

[Text version]
Cell line name FT190
Synonyms hTERT FT190; hTERT FT 190
Accession CVCL_UH57
Secondary accession CVCL_B0A3
Resource Identification Initiative To cite this cell line use: FT190 (RRID:CVCL_UH57)
Comments Doubling time: ~32 hours (ATCC=CRL-3444).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Fallopian tube; UBERON=UBERON_0003889.
Cell type: Fallopian tube secretory epithelial cell; CL=CL_4030006.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=24332043; DOI=10.1016/j.ccr.2013.10.013; PMCID=PMC3917315
Perets R., Wyant G.A., Muto K.W., Bijron J.G., Poole B.B., Chin K.T., Chen J.-Y.H., Ohman A.W., Stepule C.D., Kwak S., Karst A.M., Hirsch M.S., Setlur S.R., Crum C.P., Dinulescu D.M., Drapkin R.I.
Transformation of the fallopian tube secretory epithelium leads to high-grade serous ovarian cancer in Brca;Tp53;Pten models.
Cancer Cell 24:751-765(2013)

PubMed=26364602; DOI=10.1038/onc.2015.288; PMCID=PMC4791205
Hua G.-H., Lv X.-M., He C.-B., Remmenga S.W., Rodabaugh K.J., Dong J.-X., Yang L., Lele S.M., Yang P., Zhou J., Karst A.M., Drapkin R.I., Davis J.S., Wang C.
YAP induces high-grade serous carcinoma in fallopian tube secretory epithelial cells.
Oncogene 35:2247-2265(2016)

Cross-references
Cell line collections (Providers) ATCC; CRL-3444
Encyclopedic resources Wikidata; Q93557130
Entry history
Entry creation25-Feb-2019
Last entry update10-Apr-2025
Version number7