ID   FT190
AC   CVCL_UH57
AS   CVCL_B0A3
SY   hTERT FT190; hTERT FT 190
DR   ATCC; CRL-3444
DR   Wikidata; Q93557130
RX   PubMed=24332043;
RX   PubMed=26364602;
CC   Doubling time: ~32 hours (ATCC=CRL-3444).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Fallopian tube; UBERON=UBERON_0003889.
CC   Cell type: Fallopian tube secretory epithelial cell; CL=CL_4030006.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Age unspecified
CA   Transformed cell line
DT   Created: 25-02-19; Last updated: 10-04-25; Version: 7
//
RX   PubMed=24332043; DOI=10.1016/j.ccr.2013.10.013; PMCID=PMC3917315;
RA   Perets R., Wyant G.A., Muto K.W., Bijron J.G., Poole B.B., Chin K.T.,
RA   Chen J.-Y.H., Ohman A.W., Stepule C.D., Kwak S., Karst A.M., Hirsch M.S.,
RA   Setlur S.R., Crum C.P., Dinulescu D.M., Drapkin R.I.;
RT   "Transformation of the fallopian tube secretory epithelium leads to
RT   high-grade serous ovarian cancer in Brca;Tp53;Pten models.";
RL   Cancer Cell 24:751-765(2013).
//
RX   PubMed=26364602; DOI=10.1038/onc.2015.288; PMCID=PMC4791205;
RA   Hua G.-H., Lv X.-M., He C.-B., Remmenga S.W., Rodabaugh K.J.,
RA   Dong J.-X., Yang L., Lele S.M., Yang P., Zhou J., Karst A.M.,
RA   Drapkin R.I., Davis J.S., Wang C.;
RT   "YAP induces high-grade serous carcinoma in fallopian tube secretory
RT   epithelial cells.";
RL   Oncogene 35:2247-2265(2016).
//