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Cellosaurus HEK-Blue IL-33 (CVCL_UF59)

[Text version]
Cell line name HEK-Blue IL-33
Accession CVCL_UF59
Resource Identification Initiative To cite this cell line use: HEK-Blue IL-33 (RRID:CVCL_UF59)
Comments Characteristics: Designed to detect bioactive IL33 by monitoring the activation of the NF-kappaB and AP-1 pathways. In addition, the TNF-alpha and the IL-1beta responses have been blocked (InvivoGen).
Characteristics: SEAP (secreted ALPP) reporter cell line, in this cell line SEAP is under the control of a promoter with NF-kappaB and AP-1-binding sites.
Knockout cell: Method=Not specified; HGNC; 5993; IL1R1.
Knockout cell: Method=Not specified; HGNC; 11916; TNFRSF1A.
Knockout cell: Method=Not specified; HGNC; 11917; TNFRSF1B.
Transfected with: HGNC; 439; ALPP.
Transfected with: HGNC; 5998; IL1RL1.
Transfected with: UniProtKB; P33967; B.cereus Bsr.
Transfected with: UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Transfected with: UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Web pages https://www.invivogen.com/hek-blue-il33
Cross-references
Encyclopedic resources Wikidata; Q94092315
Entry history
Entry creation13-Nov-2018
Last entry update05-Oct-2023
Version number8