ID   HEK-Blue IL-33
AC   CVCL_UF59
DR   InvivoGen; hkb-hil33
DR   Wikidata; Q94092315
CC   Characteristics: Designed to detect bioactive IL33 by monitoring the activation of the NF-kappaB and AP-1 pathways. In addition, the TNF-alpha and the IL-1beta responses have been blocked (InvivoGen=hkb-hil33).
CC   Characteristics: SEAP (secreted ALPP) reporter cell line, in this cell line SEAP is under the control of a promoter with NF-kappaB and AP-1-binding sites (InvivoGen=hkb-hil33).
CC   Knockout cell: Method=Not specified; HGNC; HGNC:5993; IL1R1.
CC   Knockout cell: Method=Not specified; HGNC; HGNC:11916; TNFRSF1A.
CC   Knockout cell: Method=Not specified; HGNC; HGNC:11917; TNFRSF1B.
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:439; ALPP.
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:5998; IL1RL1.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P33967; B.cereus Bsr.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5.
CC   Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0045 ! HEK293
SX   Female
AG   Fetus
CA   Transformed cell line
DT   Created: 13-11-18; Last updated: 10-04-25; Version: 11
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