Cellosaurus logo
expasy logo

Cellosaurus TPP1 F/F (#35027-1) (CVCL_UE15)

[Text][XML][JSON]
Cell line name TPP1 F/F (#35027-1)
Synonyms TPP1 F/F(#35027-1)
Accession CVCL_UE15
Resource Identification Initiative To cite this cell line use: TPP1 F/F (#35027-1) (RRID:CVCL_UE15)
Comments Characteristics: Embryonic fibroblasts that have loxP sites on either side of the first-eighth coding exon of mouse Tpp1. Tpp1 knockout can be effected by transduction of Cre recombinase into the cell line (ATCC=CRL-3320).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: 129P2/Ola x C57BL/6J.
Sex of cell Sex unspecified
Age at sampling 13-14FD
Category Transformed cell line
Publications

PubMed=19995905; DOI=10.1128/mcb.01498-09; PMCID=PMC2815557
Tatsuya Kibe, Gail A. Osawa, Catherine E. Keegan, Titia de Lange;
Telomere protection by TPP1 is mediated by POT1a and POT1b.
Mol. Cell. Biol. 30:1059-1066(2010)

Cross-references
Cell line collections (Providers) ATCC; CRL-3320
Encyclopedic resources Wikidata; Q98133520
Entry history
Entry creation13-Nov-2018
Last entry update14-Aug-2025
Version number8