ID   TPP1 F/F (#35027-1)
AC   CVCL_UE15
SY   TPP1 F/F(#35027-1)
DR   ATCC; CRL-3320
DR   Wikidata; Q98133520
RX   PubMed=19995905;
CC   Characteristics: Embryonic fibroblasts that have loxP sites on either side of the first-eighth coding exon of mouse Tpp1. Tpp1 knockout can be effected by transduction of Cre recombinase into the cell line (ATCC=CRL-3320).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
CC   Cell type: Fibroblast; CL=CL_0000057.
CC   Breed/subspecies: 129P2/Ola x C57BL/6J.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   13-14FD
CA   Transformed cell line
DT   Created: 13-11-18; Last updated: 14-08-25; Version: 8
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RX   PubMed=19995905; DOI=10.1128/mcb.01498-09; PMCID=PMC2815557;
RA   Kibe, Tatsuya
RA   Osawa, Gail A.
RA   Keegan, Catherine E.
RA   de Lange, Titia
RT   "Telomere protection by TPP1 is mediated by POT1a and POT1b.";
RL   Mol. Cell. Biol. 30:1059-1066(2010).
//