Cellosaurus TRF2 F/- Rosa26-CreERT2 (CVCL_UE13)
| Cell line name | TRF2 F/- Rosa26-CreERT2 |
|---|---|
| Accession | CVCL_UE13 |
| Resource Identification Initiative | To cite this cell line use: TRF2 F/- Rosa26-CreERT2 (RRID:CVCL_UE13) |
| Comments | Characteristics: Useful in studies of telomere biology. Embryonic fibroblasts that have loxP sites on either side of the first and second coding exon of mouse Terf2. Also expresses CreERT2 from one Rosa26 locus. Terf2 knockout can be effected by transduction of Cre recombinase into the cell line (ATCC=CRL-3317). Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen. Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo. Genetic integration: Method=Transgenic mouse; Gene=MGI; MGI:1352467; Esr1 (Note=Ligand binding domain; with p.Gly525Arg. Fused to Cre = CreERT2). Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P06956; Escherichia phage P1 cre (Note=Fused to ligand domain of mouse Esr1 = CreERT2). Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). Derived from site: In situ; Embryo; UBERON=UBERON_0000922. Cell type: Fibroblast; CL=CL_0000057. |
| Species of origin | Mus musculus (Mouse)
(NCBI Taxonomy: 10090)
Breed/subspecies: 129P2/Ola x C57BL/6J. |
| Sex of cell | Sex unspecified |
| Age at sampling | 13-14FD |
| Category | Transformed cell line |
| Cross-references | |
| Cell line collections (Providers) | ATCC; CRL-3317 |
| Encyclopedic resources | Wikidata; Q98133538 |
| Entry history | |
| Entry creation | 13-Nov-2018 |
| Last entry update | 10-Apr-2025 |
| Version number | 7 |