ID   TRF2 F/- Rosa26-CreERT2
AC   CVCL_UE13
DR   ATCC; CRL-3317
DR   Wikidata; Q98133538
CC   Characteristics: Useful in studies of telomere biology. Embryonic fibroblasts that have loxP sites on either side of the first and second coding exon of mouse Terf2. Also expresses CreERT2 from one Rosa26 locus. Terf2 knockout can be effected by transduction of Cre recombinase into the cell line (ATCC=CRL-3317).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Genetic integration: Method=Transgenic mouse; Gene=MGI; MGI:1352467; Esr1 (Note=Ligand binding domain; with p.Gly525Arg. Fused to Cre = CreERT2).
CC   Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P06956; Escherichia phage P1 cre (Note=Fused to ligand domain of mouse Esr1 = CreERT2).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
CC   Cell type: Fibroblast; CL=CL_0000057.
CC   Breed/subspecies: 129P2/Ola x C57BL/6J.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   13-14FD
CA   Transformed cell line
DT   Created: 13-11-18; Last updated: 10-04-25; Version: 7
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