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Cellosaurus 143B.206 (CVCL_U923)

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Cell line name 143B.206
Synonyms 143B206; 143-B306; 143B/206; 143B.206 rho0; 143B-206rho0; 143B/206 rho0; 143B206 rho(0); 143B206 rho-zero; 206rho0
Accession CVCL_U923
Resource Identification Initiative To cite this cell line use: 143B.206 (RRID:CVCL_U923)
Comments Population: Caucasian.
Characteristics: Cell line devoid of mitochondrial DNA (rho0) (PubMed=2814477).
Derived from site: In situ; Bone, right femur; UBERON=UBERON_0000981.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Ala59Thr (c.175G>A); ClinVar=VCV000012581; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg156Pro (c.467G>C); ClinVar=VCV000634768; Zygosity=Homozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2270 (143B)
Sex of cell Female
Age at sampling 13Y
Category Cancer cell line
Publications

PubMed=2814477; DOI=10.1126/science.2814477
Michael P. King, Giuseppe Attardi;
Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementation.
Science 246:500-503(1989)

Cross-references
Cell line databases/resources cancercelllines; CVCL_U923
Encyclopedic resources Wikidata; Q54581911
Entry history
Entry creation16-Apr-2014
Last entry update19-Dec-2024
Version number19