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Cellosaurus EBC-1/brain (CVCL_U893)

[Text version]
Cell line name EBC-1/brain
Accession CVCL_U893
Resource Identification Initiative To cite this cell line use: EBC-1/brain (RRID:CVCL_U893)
Comments Population: Chinese; Taiwan.
Characteristics: Brain metastatic. Established from parent cell line in athymic mice after 5 cycles of in vivo serial passage of the cells in the mouse brain metastatic lesions.
Derived from site: Metastatic; Skin; UBERON=UBERON_0002097.
Sequence variations
  • Mutation; HGNC; 2731; DDR2; Simple; p.Thr681Ile (c.2042C>T); ClinVar=VCV001435412; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Glu171Ter (c.511G>T); ClinVar=VCV000634771; Zygosity=Homozygous (from parent cell line).
Disease Lung squamous cell carcinoma (NCIt: C3493)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2891 (EBC-1)
Sex of cell Male
Age at sampling 69Y
Category Cancer cell line
Publications

PubMed=14965364; DOI=10.1111/j.1349-7006.2004.tb03195.x; PMCID=PMC11158200
Yoshimasu T., Sakurai T., Oura S., Hirai I., Tanino H., Kokawa Y., Naito Y., Okamura Y., Ota I., Tani N., Matsuura N.
Increased expression of integrin alpha3beta1 in highly brain metastatic subclone of a human non-small cell lung cancer cell line.
Cancer Sci. 95:142-148(2004)

Cross-references
Cell line databases/resources cancercelllines; CVCL_U893
Encyclopedic resources Wikidata; Q54831759
Entry history
Entry creation16-Apr-2014
Last entry update10-Sep-2024
Version number16