ID   EBC-1/brain
AC   CVCL_U893
DR   cancercelllines; CVCL_U893
DR   Wikidata; Q54831759
RX   PubMed=14965364;
CC   Population: Japanese.
CC   Characteristics: Brain metastatic. Established from parent cell line in athymic mice after 5 cycles of in vivo serial passage of the cells in the mouse brain metastatic lesions.
CC   Sequence variation: Mutation; HGNC; 2731; DDR2; Simple; p.Thr681Ile (c.2042C>T); ClinVar=VCV001435412; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Glu171Ter (c.511G>T); ClinVar=VCV000634771; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: Metastatic; Skin; UBERON=UBERON_0002097.
DI   NCIt; C3493; Lung squamous cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_2891 ! EBC-1
SX   Male
AG   69Y
CA   Cancer cell line
DT   Created: 16-04-14; Last updated: 05-10-23; Version: 15
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RX   PubMed=14965364; DOI=10.1111/j.1349-7006.2004.tb03195.x;
RA   Yoshimasu T., Sakurai T., Oura S., Hirai I., Tanino H., Kokawa Y.,
RA   Naito Y., Okamura Y., Ota I., Tani N., Matsuura N.;
RT   "Increased expression of integrin alpha3beta1 in highly brain
RT   metastatic subclone of a human non-small cell lung cancer cell line.";
RL   Cancer Sci. 95:142-148(2004).
//