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Cellosaurus BL (CVCL_U802)

[Text version]
Cell line name BL
Synonyms BLmel; BL mel
Accession CVCL_U802
Resource Identification Initiative To cite this cell line use: BL (RRID:CVCL_U802)
Comments Omics: Transcriptome analysis by microarray.
Sequence variations
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
Web pages http://biogps.org/dataset/1409/63-melanoma-cell-lines/
Publications

PubMed=1697409
Chenevix-Trench G., Martin N.G., Ellem K.A.O.
Gene expression in melanoma cell lines and cultured melanocytes: correlation between levels of c-src-1, c-myc and p53.
Oncogene 5:1187-1193(1990)

PubMed=9331097
Salazar-Onfray F., Nakazawa T., Chhajlani V., Petersson M., Karre K., Masucci G., Celis E., Sette A., Southwood S., Appella E., Kiessling R.
Synthetic peptides derived from the melanocyte-stimulating hormone receptor MC1R can stimulate HLA-A2-restricted cytotoxic T lymphocytes that recognize naturally processed peptides on human melanoma cells.
Cancer Res. 57:4348-4355(1997)

PubMed=9354451
Castellano M., Pollock P.M., Walters M.K., Sparrow L.E., Down L.M., Gabrielli B.G., Parsons P.G., Hayward N.K.
CDKN2A/p16 is inactivated in most melanoma cell lines.
Cancer Res. 57:4868-4875(1997)

PubMed=15048078; DOI=10.1038/sj.onc.1207563
Pavey S., Johansson P., Packer L., Taylor J., Stark M.S., Pollock P.M., Walker G.J., Boyle G.M., Harper U., Cozzi S.-J., Hansen K., Yudt L., Schmidt C., Hersey P., Ellem K.A.O., O'Rourke M.G.E., Parsons P.G., Meltzer P.S., Ringner M., Hayward N.K.
Microarray expression profiling in melanoma reveals a BRAF mutation signature.
Oncogene 23:4060-4067(2004)

PubMed=15688405; DOI=10.1002/ijc.20873
Eskandarpour M., Kiaii S., Zhu C.-Y., Castro J., Sakko A.J., Hansson J.
Suppression of oncogenic NRAS by RNA interference induces apoptosis of human melanoma cells.
Int. J. Cancer 115:65-73(2005)

PubMed=17516929; DOI=10.1111/j.1600-0749.2007.00375.x
Johansson P., Pavey S., Hayward N.K.
Confirmation of a BRAF mutation-associated gene expression signature in melanoma.
Pigment Cell Res. 20:216-221(2007)

PubMed=19383913; DOI=10.1158/0008-5472.CAN-08-3746
Cedervall J., Jamil S., Prasmickaite L., Cheng Y.-F., Eskandarpour M., Hansson J., Maelandsmo G.M., Ringborg U., Gulyas M., Zhen H.-S., Kanter L., Ahrlund-Richter L.
Species-specific in vivo engraftment of the human BL melanoma cell line results in an invasive dedifferentiated phenotype not present in xenografts.
Cancer Res. 69:3746-3754(2009)

PubMed=22383533; DOI=10.1158/1535-7163.MCT-11-0676
Dutton-Regester K., Irwin D., Hunt P., Aoude L.G., Tembe V., Pupo G.M., Lanagan C., Carter C.D., O'Connor L., O'Rourke M., Scolyer R.A., Mann G.J., Schmidt C.W., Herington A., Hayward N.K.
A high-throughput panel for identifying clinically relevant mutation profiles in melanoma.
Mol. Cancer Ther. 11:888-897(2012)

PubMed=23039341; DOI=10.1186/1476-4598-11-75
Byron S.A., Loch D.C., Wellens C.L., Wortmann A., Wu J.-Y., Wang J., Nomoto K., Pollock P.M.
Sensitivity to the MEK inhibitor E6201 in melanoma cells is associated with mutant BRAF and wildtype PTEN status.
Mol. Cancer 11:75.1-75.15(2012)

Cross-references
Cell line databases/resources cancercelllines; CVCL_U802
Encyclopedic resources Wikidata; Q54797091
Gene expression databases GEO; GSM170823
Polymorphism and mutation databases Cosmic; 888987
Cosmic; 897737
Cosmic; 928724
Entry history
Entry creation16-Apr-2014
Last entry update05-Oct-2023
Version number14