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Cellosaurus BL (CVCL_U802)

[Text version]
Cell line name BL
Synonyms BLmel; BL mel
Accession CVCL_U802
Resource Identification Initiative To cite this cell line use: BL (RRID:CVCL_U802)
Comments Omics: Transcriptomics; Microarray.
Sequence variations
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=1697409
Georgia Chenevix-Trench, Nicholas Gordon Martin, Kay Adrian Oswald Ellem;
Gene expression in melanoma cell lines and cultured melanocytes: correlation between levels of c-src-1, c-myc and p53.
Oncogene 5:1187-1193(1990)

PubMed=9331097
Flavio Salazar-Onfray, Tsutomu Nakazawa, Vijay Chhajlani, Max Petersson, Klas Karre, Giuseppe Masucci, Esteban Celis, Alessandro Sette, Scott Southwood, Ettore Appella, Rolf Kiessling;
Synthetic peptides derived from the melanocyte-stimulating hormone receptor MC1R can stimulate HLA-A2-restricted cytotoxic T lymphocytes that recognize naturally processed peptides on human melanoma cells.
Cancer Res. 57:4348-4355(1997)

PubMed=9354451
Marina Castellano, Pamela M. Pollock, Marilyn K. Walters, Louise E. Sparrow, Louise M. Down, Brian G. Gabrielli, Peter G. Parsons, Nicholas K. Hayward;
CDKN2A/p16 is inactivated in most melanoma cell lines.
Cancer Res. 57:4868-4875(1997)

PubMed=15048078; DOI=10.1038/sj.onc.1207563
Sandra Pavey, Peter Johansson, Leisl Packer, Jennifer Taylor, Mitchell S. Stark, Pamela M. Pollock, Graeme J. Walker, Glen M. Boyle, Ursula Harper, Sarah-Jane Cozzi, Katherine Hansen ...Show all 20 authors... , Laura Yudt, Chris Schmidt, Peter Hersey, Kay Adrian Oswald Ellem, Michael G.E. O'Rourke, Peter G. Parsons, Paul S. Meltzer, Markus Ringner, Nicholas K. Hayward; Show fewer authors
Microarray expression profiling in melanoma reveals a BRAF mutation signature.
Oncogene 23:4060-4067(2004)

PubMed=15688405; DOI=10.1002/ijc.20873
Malihe Eskandarpour, Shahryar Kiaii, Chao-Yong Zhu, Juan Castro, Andrew J. Sakko, Johan Hansson;
Suppression of oncogenic NRAS by RNA interference induces apoptosis of human melanoma cells.
Int. J. Cancer 115:65-73(2005)

PubMed=17516929; DOI=10.1111/j.1600-0749.2007.00375.x
Peter Johansson, Sandra Pavey, Nicholas K. Hayward;
Confirmation of a BRAF mutation-associated gene expression signature in melanoma.
Pigment Cell Res. 20:216-221(2007)

PubMed=19383913; DOI=10.1158/0008-5472.CAN-08-3746
Jessica Cedervall, Seema Jamil, Lina Prasmickaite, Yen-Fu Cheng, Malihe Eskandarpour, Johan Hansson, Gunhild Mari Maelandsmo, Ulrik Ringborg, Miklos Gulyas, He-Suo Zhen, Lena Kanter, Lars Ahrlund-Richter;
Species-specific in vivo engraftment of the human BL melanoma cell line results in an invasive dedifferentiated phenotype not present in xenografts.
Cancer Res. 69:3746-3754(2009)

PubMed=22383533; DOI=10.1158/1535-7163.MCT-11-0676
Ken Dutton-Regester, Darryl Irwin, Priscilla Hunt, Lauren G. Aoude, Varsha Tembe, Gulietta M. Pupo, Cathy Lanagan, Candace D. Carter, Linda O'Connor, Michael O'Rourke, Richard Anthony Scolyer ...Show all 15 authors... , Graham J. Mann, Christopher W. Schmidt, Adrian Herington, Nicholas K. Hayward; Show fewer authors
A high-throughput panel for identifying clinically relevant mutation profiles in melanoma.
Mol. Cancer Ther. 11:888-897(2012)

PubMed=23039341; DOI=10.1186/1476-4598-11-75; PMCID=PMC3554420
Sara A. Byron, David C. Loch, Candice L. Wellens, Andreas Wortmann, Jia-Yi Wu, John Wang, Kenichi Nomoto, Pamela M. Pollock;
Sensitivity to the MEK inhibitor E6201 in melanoma cells is associated with mutant BRAF and wildtype PTEN status.
Mol. Cancer 11:75.1-75.15(2012)

Cross-references
Cell line databases/resources cancercelllines; CVCL_U802
Encyclopedic resources Wikidata; Q54797091
Gene expression databases GEO; GSM170823
Polymorphism and mutation databases Cosmic; 888987
Cosmic; 897737
Cosmic; 928724
Entry history
Entry creation16-Apr-2014
Last entry update14-Aug-2025
Version number17