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Cellosaurus CHU-2 (CVCL_U416)

[Text version]
Cell line name CHU-2
Accession CVCL_U416
Resource Identification Initiative To cite this cell line use: CHU-2 (RRID:CVCL_U416)
Comments Population: Japanese.
Characteristics: Secretes large amount of CSF3 (PubMed=3487449).
Characteristics: Established after the 9th passage of the original tumor cell in nude mice (PubMed=3487449).
Doubling time: ~20 hours (PubMed=3487449).
Derived from site: In situ; Oral cavity; UBERON=UBERON_0000167.
Cell type: Epithelial cell; CL=CL_0000066.
Disease Oral cavity squamous cell carcinoma (NCIt: C4833)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Web pages Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/c/cell-lines-detail-427.html
Publications

PubMed=3487449; DOI=10.1002/j.1460-2075.1986.tb04297.x; PMCID=PMC1166876
Nomura H., Imazeki I., Oheda M., Kubota N., Tamura M., Ono M., Ueyama Y., Asano S.
Purification and characterization of human granulocyte colony-stimulating factor (G-CSF).
EMBO J. 5:871-876(1986)

PubMed=1714402
Akatsuka A., Shimamura K., Katoh Y., Takekoshi S., Nakamura M., Nomura H., Hasegawa M., Ueyama Y., Tamaoki N.
Electron microscopic identification of the intracellular secretion pathway of human G-CSF in a human tumor cell line: a comparative study with a Chinese hamster ovary cell line (IA1-7) transfected with human G-CSF cDNA.
Exp. Hematol. 19:768-772(1991)

PubMed=7691144; DOI=10.1038/bjc.1993.416; PMCID=PMC1968588
Katoh Y., Nakamura M., Ohnishi Y., Shimamura K., Ueyama Y., Tamaoki N.
Autonomous production of granulocyte-colony stimulating factor in tumour xenografts associated with leukocytosis.
Br. J. Cancer 68:715-719(1993)

Cross-references
Encyclopedic resources Wikidata; Q54813323
Entry history
Entry creation03-Feb-2014
Last entry update10-Apr-2025
Version number11