ID   CHU-2
AC   CVCL_U416
DR   Wikidata; Q54813323
RX   PubMed=1714402;
RX   PubMed=3487449;
RX   PubMed=7691144;
WW   Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/c/cell-lines-detail-427.html
CC   Population: Japanese.
CC   Characteristics: Secretes large amount of CSF3 (PubMed=3487449).
CC   Characteristics: Established after the 9th passage of the original tumor cell in nude mice (PubMed=3487449).
CC   Doubling time: ~20 hours (PubMed=3487449).
CC   Derived from site: In situ; Oral cavity; UBERON=UBERON_0000167.
CC   Cell type: Epithelial cell; CL=CL_0000066.
DI   NCIt; C4833; Oral cavity squamous cell carcinoma
DI   ORDO; Orphanet_502363; Squamous cell carcinoma of the oral cavity
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Age unspecified
CA   Cancer cell line
DT   Created: 03-02-14; Last updated: 10-04-25; Version: 11
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RX   PubMed=1714402;
RA   Akatsuka A., Shimamura K., Katoh Y., Takekoshi S., Nakamura M.,
RA   Nomura H., Hasegawa M., Ueyama Y., Tamaoki N.;
RT   "Electron microscopic identification of the intracellular secretion
RT   pathway of human G-CSF in a human tumor cell line: a comparative study
RT   with a Chinese hamster ovary cell line (IA1-7) transfected with human
RT   G-CSF cDNA.";
RL   Exp. Hematol. 19:768-772(1991).
//
RX   PubMed=3487449; DOI=10.1002/j.1460-2075.1986.tb04297.x; PMCID=PMC1166876;
RA   Nomura H., Imazeki I., Oheda M., Kubota N., Tamura M., Ono M.,
RA   Ueyama Y., Asano S.;
RT   "Purification and characterization of human granulocyte
RT   colony-stimulating factor (G-CSF).";
RL   EMBO J. 5:871-876(1986).
//
RX   PubMed=7691144; DOI=10.1038/bjc.1993.416; PMCID=PMC1968588;
RA   Katoh Y., Nakamura M., Ohnishi Y., Shimamura K., Ueyama Y.,
RA   Tamaoki N.;
RT   "Autonomous production of granulocyte-colony stimulating factor in
RT   tumour xenografts associated with leukocytosis.";
RL   Br. J. Cancer 68:715-719(1993).
//