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Cellosaurus PC-9/f14 (CVCL_U149)

[Text version]
Cell line name PC-9/f14
Accession CVCL_U149
Resource Identification Initiative To cite this cell line use: PC-9/f14 (RRID:CVCL_U149)
Comments Population: Japanese.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
Sequence variations
  • Mutation; HGNC; 3236; EGFR; Simple; p.Glu746_Ala750del (c.2235_2249del15); ClinVar=VCV000163343; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_B260 (PC-9)
Sex of cell Male
Age at sampling 45Y
Category Cancer cell line

PubMed=11506965; DOI=10.1016/S0959-8049(01)00154-X
Gemma A., Takenaka K., Hosoya Y., Matuda K., Seike M., Kurimoto F., Ono Y., Uematsu K., Takeda Y., Hibino S., Yoshimura A., Shibuya M., Kudoh S.
Altered expression of several genes in highly metastatic subpopulations of a human pulmonary adenocarcinoma cell line.
Eur. J. Cancer 37:1554-1561(2001)

PubMed=17982658; DOI=10.3892/ijo.31.6.1325
Takemura A., Gemma A., Shibuya M., Matsuda K., Okano T., Nara M., Noro R., Minegishi Y., Yoshimura A., Kudoh S.
Gemcitabine resistance in a highly metastatic subpopulation of a pulmonary adenocarcinoma cell line resistant to gefitinib.
Int. J. Oncol. 31:1325-1332(2007)

Cell line databases/resources cancercelllines; CVCL_U149
Encyclopedic resources Wikidata; Q54938492
Polymorphism and mutation databases Cosmic; 915331
Entry history
Entry creation03-Feb-2014
Last entry update05-Oct-2023
Version number16