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Cellosaurus G603L (CVCL_U091)

[Text version]
Cell line name G603L
Accession CVCL_U091
Resource Identification Initiative To cite this cell line use: G603L (RRID:CVCL_U091)
Comments Population: Japanese.
Doubling time: 23 hours (PubMed=15573370).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; 3236; EGFR; Simple; p.Leu858Arg (c.2573T>G); ClinVar=VCV000016609; Zygosity=Unspecified (PubMed=21498706).
HLA typing Source: PubMed=17131342
Class I
HLA-AA*26:02,31:012
HLA-BB*15:01,40:02
HLA-CC*03:03,03:04
Disease Lung pleomorphic carcinoma (NCIt: C45542)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_U090 ! G603AD
CVCL_TZ77 ! G603EBV-B
Sex of cell Male
Age at sampling 75Y
Category Cancer cell line
Publications

PubMed=15573370; DOI=10.1002/cncr.20782
So T., Takenoyama M., Ichiki Y., Mizukami M., So T., Hanagiri T., Sugio K., Yasumoto K.
A different pattern of cytotoxic T lymphocyte recognition against primary and metastatic tumor cells in a patient with nonsmall cell lung carcinoma.
Cancer 103:200-208(2005)

PubMed=16651449; DOI=10.1158/0008-5472.CAN-05-3840
Fukuyama T., Hanagiri T., Takenoyama M., Ichiki Y., Mizukami M., So T., Sugaya M., So T., Sugio K., Yasumoto K.
Identification of a new cancer/germline gene, KK-LC-1, encoding an antigen recognized by autologous CTL induced on human lung adenocarcinoma.
Cancer Res. 66:4922-4928(2006)

PubMed=17131342; DOI=10.1002/ijc.22396
Sugaya M., Takenoyama M., Shigematsu Y., Baba T., Fukuyama T., Nagata Y., Mizukami M., So T., Ichiki Y., Yasuda M., So T., Hanagiri T., Sugio K., Yasumoto K.
Identification of HLA-A24 restricted shared antigen recognized by autologous cytotoxic T lymphocytes from a patient with large cell carcinoma of the lung.
Int. J. Cancer 120:1055-1062(2007)

PubMed=17511773; DOI=10.1111/j.1349-7006.2007.00507.x
Fukuyama T., Ichiki Y., Yamada S., Shigematsu Y., Baba T., Nagata Y., Mizukami M., Sugaya M., Takenoyama M., Hanagiri T., Sugio K., Yasumoto K.
Cytokine production of lung cancer cell lines: correlation between their production and the inflammatory/immunological responses both in vivo and in vitro.
Cancer Sci. 98:1048-1054(2007)

PubMed=17725806; DOI=10.1111/j.1349-7006.2007.00586.x
Baba T., Hanagiri T., Ichiki Y., Kuroda K., Shigematsu Y., Mizukami M., Sugaya M., Takenoyama M., Sugio K., Yasumoto K.
Lack and restoration of sensitivity of lung cancer cells to cellular attack with special reference to expression of human leukocyte antigen class I and/or major histocompatibility complex class I chain related molecules A/B.
Cancer Sci. 98:1795-1802(2007)

PubMed=21498706
Onitsuka T., Uramoto H., Tanaka F.
Lack of direct association between EGFR mutations and ER beta expression in lung cancer.
Anticancer Res. 31:855-860(2011)

Cross-references
Cell line collections (Providers) RCB; RCB3529
Cell line databases/resources cancercelllines; CVCL_U091
Encyclopedic resources Wikidata; Q54835410
Polymorphism and mutation databases Cosmic; 1513407
Entry history
Entry creation03-Feb-2014
Last entry update05-Oct-2023
Version number12