ID   G603L
AC   CVCL_U091
DR   cancercelllines; CVCL_U091
DR   Cosmic; 1513407
DR   RCB; RCB3529
DR   Wikidata; Q54835410
RX   PubMed=15573370;
RX   PubMed=16651449;
RX   PubMed=17131342;
RX   PubMed=17511773;
RX   PubMed=17725806;
RX   PubMed=21498706;
CC   Population: Japanese.
CC   Doubling time: 23 hours (PubMed=15573370).
CC   HLA typing: A*26:02,31:012; B*15:01,40:02; C*03:03,03:04 (PubMed=17131342).
CC   Sequence variation: Mutation; HGNC; 3236; EGFR; Simple; p.Leu858Arg (c.2573T>G); ClinVar=VCV000016609; Zygosity=Unspecified (PubMed=21498706).
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
DI   NCIt; C45542; Lung pleomorphic carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_U090 ! G603AD
OI   CVCL_TZ77 ! G603EBV-B
SX   Male
AG   75Y
CA   Cancer cell line
DT   Created: 03-02-14; Last updated: 05-10-23; Version: 12
//
RX   PubMed=15573370; DOI=10.1002/cncr.20782;
RA   So T., Takenoyama M., Ichiki Y., Mizukami M., So T., Hanagiri T.,
RA   Sugio K., Yasumoto K.;
RT   "A different pattern of cytotoxic T lymphocyte recognition against
RT   primary and metastatic tumor cells in a patient with nonsmall cell
RT   lung carcinoma.";
RL   Cancer 103:200-208(2005).
//
RX   PubMed=16651449; DOI=10.1158/0008-5472.CAN-05-3840;
RA   Fukuyama T., Hanagiri T., Takenoyama M., Ichiki Y., Mizukami M.,
RA   So T., Sugaya M., So T., Sugio K., Yasumoto K.;
RT   "Identification of a new cancer/germline gene, KK-LC-1, encoding an
RT   antigen recognized by autologous CTL induced on human lung
RT   adenocarcinoma.";
RL   Cancer Res. 66:4922-4928(2006).
//
RX   PubMed=17131342; DOI=10.1002/ijc.22396;
RA   Sugaya M., Takenoyama M., Shigematsu Y., Baba T., Fukuyama T.,
RA   Nagata Y., Mizukami M., So T., Ichiki Y., Yasuda M., So T.,
RA   Hanagiri T., Sugio K., Yasumoto K.;
RT   "Identification of HLA-A24 restricted shared antigen recognized by
RT   autologous cytotoxic T lymphocytes from a patient with large cell
RT   carcinoma of the lung.";
RL   Int. J. Cancer 120:1055-1062(2007).
//
RX   PubMed=17511773; DOI=10.1111/j.1349-7006.2007.00507.x;
RA   Fukuyama T., Ichiki Y., Yamada S., Shigematsu Y., Baba T., Nagata Y.,
RA   Mizukami M., Sugaya M., Takenoyama M., Hanagiri T., Sugio K.,
RA   Yasumoto K.;
RT   "Cytokine production of lung cancer cell lines: correlation between
RT   their production and the inflammatory/immunological responses both in
RT   vivo and in vitro.";
RL   Cancer Sci. 98:1048-1054(2007).
//
RX   PubMed=17725806; DOI=10.1111/j.1349-7006.2007.00586.x;
RA   Baba T., Hanagiri T., Ichiki Y., Kuroda K., Shigematsu Y.,
RA   Mizukami M., Sugaya M., Takenoyama M., Sugio K., Yasumoto K.;
RT   "Lack and restoration of sensitivity of lung cancer cells to cellular
RT   attack with special reference to expression of human leukocyte
RT   antigen class I and/or major histocompatibility complex class I chain
RT   related molecules A/B.";
RL   Cancer Sci. 98:1795-1802(2007).
//
RX   PubMed=21498706;
RA   Onitsuka T., Uramoto H., Tanaka F.;
RT   "Lack of direct association between EGFR mutations and ER beta
RT   expression in lung cancer.";
RL   Anticancer Res. 31:855-860(2011).
//