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Cellosaurus GPNT (CVCL_T962)

[Text version]
Cell line name GPNT
Synonyms GP8 NeuroTech
Accession CVCL_T962
Resource Identification Initiative To cite this cell line use: GPNT (RRID:CVCL_T962)
Comments Doubling time: ~10 hours (ECACC=09061601).
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
Derived from site: In situ; Brain, cerebral cortex; UBERON=UBERON_0000956.
Cell type: Endothelial cell of cerebral cortex; CL=CL_1001602.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Lewis; RS=RS_0000121.
Hierarchy Parent: CVCL_T959 (GP8.3)
Sex of cell Female
Age at sampling 4-6W
Category Transformed cell line
Publications

PubMed=10537053; DOI=10.1046/j.1471-4159.1999.01954.x
Regina A., Romero I.A., Greenwood J., Adamson P., Bourre J.-M., Couraud P.-O., Roux F.
Dexamethasone regulation of P-glycoprotein activity in an immortalized rat brain endothelial cell line, GPNT.
J. Neurochem. 73:1954-1963(1999)

Cross-references
Cell line collections (Providers) ABM; T0685
ECACC; 09061601
Encyclopedic resources Wikidata; Q54871646
Entry history
Entry creation03-Feb-2014
Last entry update10-Apr-2025
Version number15