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Cellosaurus cen3tel (CVCL_S896)

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Cell line name cen3tel
Synonyms Cen3tel; Cen3 tel
Accession CVCL_S896
Resource Identification Initiative To cite this cell line use: cen3tel (RRID:CVCL_S896)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_B5SM (cen3)
Sex of cell Female
Age at sampling 102Y
Category Telomerase immortalized cell line
Publications

PubMed=12927806; DOI=10.1016/S0006-291X(03)01484-0
Chiara Mondello, Massimo Chiesa, Paola Rebuzzini, Samantha Zongaro, Annalisa Verri, Tina Colombo, Elena Giulotto, Maurizio D'Incalci, Claudio Franceschi, Fiorella Nuzzo;
Karyotype instability and anchorage-independent growth in telomerase-immortalized fibroblasts from two centenarian individuals.
Biochem. Biophys. Res. Commun. 308:914-921(2003)

PubMed=16357149; DOI=10.1158/0008-5472.CAN-05-1140
Samantha Zongaro, Elisa de Stanchina, Tina Colombo, Maurizio D'Incalci, Elena Giulotto, Chiara Mondello;
Stepwise neoplastic transformation of a telomerase immortalized fibroblast cell line.
Cancer Res. 65:11411-11418(2005)

PubMed=21209796; DOI=10.1371/journal.pone.0014154; PMCID=PMC3014295
Cristina Belgiovine, Roberta Frapolli, Katiuscia Bonezzi, Ilaria Chiodi, Francesco Favero, Maurizia Mello-Grand, Angelo P. Dei Tos, Elena Giulotto, Giulia Taraboletti, Maurizio D'Incalci, Chiara Mondello;
Reduced expression of the ROCK inhibitor Rnd3 is associated with increased invasiveness and metastatic potential in mesenchymal tumor cells.
PLoS ONE 5:e14154.1-e14154.10(2010)

Cross-references
Encyclopedic resources Wikidata; Q54809292
Gene expression databases GEO; GSE15742
Entry history
Entry creation03-Feb-2014
Last entry update14-Aug-2025
Version number11