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Cellosaurus HROC87 T0 M2 (CVCL_S854)

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Cell line name HROC87 T0 M2
Synonyms HROC87; HROC87X
Accession CVCL_S854
Resource Identification Initiative To cite this cell line use: HROC87 T0 M2 (RRID:CVCL_S854)
Comments From: Linnebacher, Michael; University of Rostock; Rostock; Germany.
Population: Caucasian.
Characteristics: Established from a patient-derived xenograft established in female NMRI nu/nu mice.
Doubling time: 26 hours (CLS=300831).
Microsatellite instability: Instable (MSI) (PubMed=25926053).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Colon, ascending; UBERON=UBERON_0001156.
Sequence variations
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 76Y
Category Cancer cell line
STR profile Source(s): CLS=300831; Direct_author_submission; PubMed=25926053

Markers:
AmelogeninX
CSF1PO12
D5S8189,11
D7S8209
D13S31710 (Direct_author_submission)
10,14 (CLS=300831; PubMed=25926053)
D16S53911,13
D21S1128,29
TH018
TPOX11,13
vWA16,20

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Publications

PubMed=23300683; DOI=10.1371/journal.pone.0052485; PMCID=PMC3534085
Claudia Maletzki, Saskia Stier, Ulrike Gruenert, Michael Gock, Christiane Ostwald, Friedrich Prall, Michael Linnebacher;
Establishment, characterization and chemosensitivity of three mismatch repair deficient cell lines from sporadic and inherited colorectal carcinomas.
PLoS ONE 7:e52485.1-e52485.12(2012)

PubMed=25926053; DOI=10.1038/ncomms8002
Enzo Medico, Mariangela Russo, Gabriele Picco, Carlotta Cancelliere, Emanuele Valtorta, Giorgio Corti, Michela Buscarino, Claudio Isella, Simona Lamba, Barbara Martinoglio, Silvio Veronese ...Show all 19 authors... , Salvatore Siena, Andrea Sartore-Bianchi, Marco Beccuti, Marcella Mottolese, Michael Linnebacher, Francesca Cordero, Federica Di Nicolantonio, Alberto Bardelli; Show fewer authors
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Nat. Commun. 6:7002.1-7002.10(2015)

PubMed=31601052; DOI=10.3390/cancers11101520; PMCID=PMC6826890
Christina Susanne Mullins, Bianca Micheel, Stephanie Matschos, Matthias Leuchter, Florian Burtin, Mathias Krohn, Maja Huhns, Ernst Klar, Friedrich Prall, Michael Linnebacher;
Integrated biobanking and tumor model establishment of human colorectal carcinoma provides excellent tools for preclinical research.
Cancers (Basel) 11:1520.1-1520.18(2019)

Cross-references
Cell line collections (Providers) CLS; 300831
Cell line databases/resources cancercelllines; CVCL_S854
Encyclopedic resources Wikidata; Q54895306
Gene expression databases GEO; GSM1448072
Entry history
Entry creation03-Feb-2014
Last entry update10-Apr-2025
Version number26