| Cell line name |
H69VZ |
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| Synonyms |
MOG-H69VZ |
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| Accession |
CVCL_S830 |
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| Resource Identification Initiative |
To cite this cell line use: H69VZ (RRID:CVCL_S830) |
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| Comments |
Doubling time: 34.5 hours (PubMed=1662924). |
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| Sequence variations |
- Mutation; HGNC; 8975; PIK3CA; Simple; p.Gly106_Arg108del (c.317_325delGGCAACCGT); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 9884; RB1; Simple; p.Glu748Ter (c.2242G>T); ClinVar=VCV000013078; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.Glu171Ter (c.511G>T); ClinVar=VCV000634771; Zygosity=Homozygous (from parent cell line).
|
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| Disease |
Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Derived from metastatic site: Pleural effusion. |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_1579 (NCI-H69) |
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| Sex of cell |
Male |
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| Age at sampling |
55Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=1662924
Khan M.Z., Freshney R.I., Murray A.M.B., Merry S., Plumb J.A., McNicol A.M.
Identification and characterisation in vitro of cells with a non-SCLC cell-like phenotype derived from a continuous SCLC cell line.
Anticancer Res. 11:1687-1695(1991) PubMed=8712684
Khan M.Z., McNicol A.M., Freshney R.I.
Tumorigenicity, invasion and metastasis of the small cell lung cancer cell line NCI-H69 and two derivative lines MOG-H69V and MOG-H69VZ.
Anticancer Res. 16:1659-1669(1996) |
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| Cross-references |
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| Encyclopedic resources |
Wikidata; Q54872209
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| Entry history |
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| Entry creation | 03-Feb-2014 |
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| Last entry update | 15-Dec-2022 |
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| Version number | 15 |
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