ID   H69VZ
AC   CVCL_S830
SY   MOG-H69VZ
DR   cancercelllines; CVCL_S830
DR   Wikidata; Q54872209
RX   PubMed=1662924;
RX   PubMed=8712684;
CC   Population: Caucasian.
CC   Doubling time: 34.5 hours (PubMed=1662924).
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.Gly106_Arg108del (c.317_325delGGCAACCGT); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 9884; RB1; Simple; p.Glu748Ter (c.2242G>T); ClinVar=VCV000013078; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Glu171Ter (c.511G>T); ClinVar=VCV000634771; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C4917; Lung small cell carcinoma
DI   ORDO; Orphanet_70573; Small cell lung cancer
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1579 ! NCI-H69
SX   Male
AG   55Y
CA   Cancer cell line
DT   Created: 03-02-14; Last updated: 05-10-23; Version: 18
//
RX   PubMed=1662924;
RA   Khan M.Z., Freshney R.I., Murray A.M.B., Merry S., Plumb J.A.,
RA   McNicol A.M.;
RT   "Identification and characterisation in vitro of cells with a non-SCLC
RT   cell-like phenotype derived from a continuous SCLC cell line.";
RL   Anticancer Res. 11:1687-1695(1991).
//
RX   PubMed=8712684;
RA   Khan M.Z., McNicol A.M., Freshney R.I.;
RT   "Tumorigenicity, invasion and metastasis of the small cell lung cancer
RT   cell line NCI-H69 and two derivative lines MOG-H69V and MOG-H69VZ.";
RL   Anticancer Res. 16:1659-1669(1996).
//