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Cellosaurus AY-27 (CVCL_S825)

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Cell line name AY-27
Synonyms AY 27; AY27
Accession CVCL_S825
Resource Identification Initiative To cite this cell line use: AY-27 (RRID:CVCL_S825)
Comments Characteristics: Tumorigenic.
Doubling time: 0.927 +- 0.206 days (PubMed=2936252).
Transformant: ChEBI; CHEBI_82328; Nifurthiazole (N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide; FANFT).
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Disease Transitional cell carcinoma of the rat urinary bladder (NCIt: C64161)
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Fischer 344; RS=RS_0000215.
Sex of cell Male
Category Cancer cell line
Publications

PubMed=7298281
Samuel Monroe Cohen, James P.S. Yang, Jerome B. Jacobs, Masayuki Arai, Shoji Fukushima, Gilbert H. Friedell;
Transplantation and cell culture of rat urinary bladder carcinoma.
Invest. Urol. 19:136-141(1981)

PubMed=2981157
Francis J. Chlapowski, Georgina M. Nemecek;
Aberrant cyclic adenosine 3':5'-monophosphate metabolism in cultures of tumorigenic rat urothelium.
Cancer Res. 45:122-127(1985)

PubMed=2936252; PMCID=PMC1888108
Janine R. Shulok, James Edward Klaunig, Steven H. Selman, Patrick J. Schafer, Peter J. Goldblatt;
Cellular effects of hematoporphyrin derivative photodynamic therapy on normal and neoplastic rat bladder cells.
Am. J. Pathol. 122:277-283(1986)

PubMed=10574249; DOI=10.1038/sj.bjc.6690741; PMCID=PMC2362887
Zheng-Wen Xiao, Theresa J. McCallum, Kevin M. Brown, Gerald G. Miller, Steven B. Halls, Ian Frederick Parney, Ronald B. Moore;
Characterization of a novel transplantable orthotopic rat bladder transitional cell tumour model.
Br. J. Cancer 81:638-646(1999)

PubMed=20404568; DOI=10.4161/cbt.9.12.11638
Joachim Vandepitte, Jan Maes, Ben Van Cleynenbreugel, Hein Van Poppel, Evelyne Lerut, Patrizia Agostinis, Peter A.M. de Witte;
An improved orthotopic rat bladder tumor model using Dil-loaded fluorescent AY-27 cells.
Cancer Biol. Ther. 9:986-993(2010)

PubMed=21424013; DOI=10.1039/c0pp00393j
Ingvild Kinn Ekroll, Odrun Arna Gederaas, Linda Helander, Astrid Hjelde, Thor Bernt Melo, Anders Johnsson;
Photo induced hexylaminolevulinate destruction of rat bladder cells AY-27.
Photochem. Photobiol. Sci. 10:1072-1079(2011)

PubMed=29732388; DOI=10.3233/BLC-180167; PMCID=PMC5929350
Tahlita C.M. Zuiverloon, Florus Christiaan de Jong, James C. Costello, Dan Theodorescu;
Systematic review: characteristics and preclinical uses of bladder cancer cell lines.
Bladder Cancer 4:169-183(2018)

Cross-references
Cell line collections (Providers) Millipore; SCC254
Chemistry resources ChEMBL-Cells; CHEMBL4482253
PubChem_Cell_line; CVCL_S825
Encyclopedic resources Wikidata; Q54752001
Entry history
Entry creation03-Feb-2014
Last entry update10-Apr-2025
Version number14