ID   AY-27
AC   CVCL_S825
SY   AY 27; AY27
DR   ChEMBL-Cells; CHEMBL4482253
DR   Millipore; SCC254
DR   PubChem_Cell_line; CVCL_S825
DR   Wikidata; Q54752001
RX   PubMed=2936252;
RX   PubMed=2981157;
RX   PubMed=7298281;
RX   PubMed=10574249;
RX   PubMed=20404568;
RX   PubMed=21424013;
RX   PubMed=29732388;
CC   Characteristics: Tumorigenic.
CC   Doubling time: 0.927 +- 0.206 days (PubMed=2936252).
CC   Transformant: ChEBI; CHEBI_82328; Nifurthiazole (N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide; FANFT).
CC   Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
CC   Breed/subspecies: Fischer 344; RS=RS_0000215.
DI   NCIt; C64161; Transitional cell carcinoma of the rat urinary bladder
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
SX   Male
CA   Cancer cell line
DT   Created: 03-02-14; Last updated: 10-04-25; Version: 14
//
RX   PubMed=2936252; PMCID=PMC1888108;
RA   Shulok, Janine R.
RA   Klaunig, James Edward
RA   Selman, Steven H.
RA   Schafer, Patrick J.
RA   Goldblatt, Peter J.
RT   "Cellular effects of hematoporphyrin derivative photodynamic therapy
RT   on normal and neoplastic rat bladder cells.";
RL   Am. J. Pathol. 122:277-283(1986).
//
RX   PubMed=21424013; DOI=10.1039/c0pp00393j;
RA   Ekroll, Ingvild Kinn
RA   Gederaas, Odrun Arna
RA   Helander, Linda
RA   Hjelde, Astrid
RA   Melo, Thor Bernt
RA   Johnsson, Anders
RT   "Photo induced hexylaminolevulinate destruction of rat bladder cells
RT   AY-27.";
RL   Photochem. Photobiol. Sci. 10:1072-1079(2011).
//
RX   PubMed=7298281;
RA   Cohen, Samuel Monroe
RA   Yang, James P.S.
RA   Jacobs, Jerome B.
RA   Arai, Masayuki
RA   Fukushima, Shoji
RA   Friedell, Gilbert H.
RT   "Transplantation and cell culture of rat urinary bladder carcinoma.";
RL   Invest. Urol. 19:136-141(1981).
//
RX   PubMed=29732388; DOI=10.3233/BLC-180167; PMCID=PMC5929350;
RA   Zuiverloon, Tahlita C.M.
RA   de Jong, Florus Christiaan
RA   Costello, James C.
RA   Theodorescu, Dan
RT   "Systematic review: characteristics and preclinical uses of bladder
RT   cancer cell lines.";
RL   Bladder Cancer 4:169-183(2018).
//
RX   PubMed=10574249; DOI=10.1038/sj.bjc.6690741; PMCID=PMC2362887;
RA   Xiao, Zheng-Wen
RA   McCallum, Theresa J.
RA   Brown, Kevin M.
RA   Miller, Gerald G.
RA   Halls, Steven B.
RA   Parney, Ian Frederick
RA   Moore, Ronald B.
RT   "Characterization of a novel transplantable orthotopic rat bladder
RT   transitional cell tumour model.";
RL   Br. J. Cancer 81:638-646(1999).
//
RX   PubMed=20404568; DOI=10.4161/cbt.9.12.11638;
RA   Vandepitte, Joachim
RA   Maes, Jan
RA   Van Cleynenbreugel, Ben
RA   Van Poppel, Hein
RA   Lerut, Evelyne
RA   Agostinis, Patrizia
RA   de Witte, Peter A.M.
RT   "An improved orthotopic rat bladder tumor model using Dil-loaded
RT   fluorescent AY-27 cells.";
RL   Cancer Biol. Ther. 9:986-993(2010).
//
RX   PubMed=2981157;
RA   Chlapowski, Francis J.
RA   Nemecek, Georgina M.
RT   "Aberrant cyclic adenosine 3':5'-monophosphate metabolism in cultures
RT   of tumorigenic rat urothelium.";
RL   Cancer Res. 45:122-127(1985).
//