Cellosaurus logo
expasy logo

Cellosaurus 1765-92 (CVCL_S817)

[Text version]
Cell line name 1765-92
Synonyms MLS 1765-92; MLS-1765; MLS1765
Accession CVCL_S817
Resource Identification Initiative To cite this cell line use: 1765-92 (RRID:CVCL_S817)
Comments Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Sequence variations
  • Gene fusion; HGNC; HGNC:2726; DDIT3 + HGNC; HGNC:4010; FUS; Name(s)=FUS-DDIT3, TLS-CHOP (PubMed=27270875).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=27270875).
Disease Myxoid liposarcoma (NCIt: C27781)
Myxoid/round cell liposarcoma (ORDO: Orphanet_99967)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Transformed cell line
Publications

PubMed=16983332; DOI=10.1038/sj.onc.1209996
Marco M. Candeias, Darren J. Powell, Eva Roubalova, Sebastien Apcher, Karima Bourougaa, Borivoj Vojtesek, Heriberto Bruzzoni-Giovanelli, Robin Fahraeus;
Expression of p53 and p53/47 are controlled by alternative mechanisms of messenger RNA translation initiation.
Oncogene 25:6936-6947(2006)

PubMed=20515481; DOI=10.1186/1471-2407-10-249; PMCID=PMC2889895
Mattias K. Andersson, Melker Goransson, Anita Olofsson, Carola Andersson, Pierre Aman;
Nuclear expression of FLT1 and its ligand PGF in FUS-DDIT3 carrying myxoid liposarcomas suggests the existence of an intracrine signaling loop.
BMC Cancer 10:249.1-249.10(2010)

PubMed=24726063; DOI=10.1186/1756-9966-33-33; PMCID=PMC4022359
Christian Koelsche, Marcus Renner, Wolfgang Hartmann, Regine Brandt, Burkhard Lehner, Nina Waldburger, Ingo Alldinger, Thomas Schmitt, Gerlinde Egerer, Roland Penzel, Eva Wardelmann ...Show all 14 authors... , Peter Schirmacher, Andreas von Deimling, Gunhild Mechtersheimer; Show fewer authors
TERT promoter hotspot mutations are recurrent in myxoid liposarcomas but rare in other soft tissue sarcoma entities.
J. Exp. Clin. Cancer Res. 33:33.1-33.8(2014)

PubMed=25393000; DOI=10.1371/journal.pone.0113110; PMCID=PMC4231113
Anders Stahlberg, Christina Kabjorn-Gustafsson, Katarina Engtrom, Christer Thomsen, Soheila Dolatabadi, Emma Jonasson, Chieh-Yuan Li, David Ruff, Shiaw-Min Chen, Pierre Aman;
Normal and functional TP53 in genetically stable myxoid/round cell liposarcoma.
PLoS ONE 9:e113110.1-e113110.7(2014)

PubMed=27270875; DOI=10.1038/labinvest.2016.64; PMCID=PMC4965313
Marieke A. de Graaff, Jamie S.E. Yu, Hannah C. Beird, Davis R. Ingram, Theresa Nguyen, Jeffrey Jue-Hui Liu, Svetlana V. Bolshakov, Karoly Szuhai, Pierre Aman, Keila Enitt Torres, Dina Chelouche Lev ...Show all 15 authors... , Torsten O. Nielsen, Judith V.M.G. Bovee, Alexander J.F. Lazar, Neeta Somaiah; Show fewer authors
Establishment and characterization of a new human myxoid liposarcoma cell line (DL-221) with the FUS-DDIT3 translocation.
Lab. Invest. 96:885-894(2016)

Cross-references
Encyclopedic resources Wikidata; Q54582361
Polymorphism and mutation databases Cosmic; 1672268
Cosmic; 2307720
Entry history
Entry creation03-Feb-2014
Last entry update19-Dec-2024
Version number15