| Cell line name |
402-91/ET |
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| Accession |
CVCL_S814 |
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| Resource Identification Initiative |
To cite this cell line use: 402-91/ET (RRID:CVCL_S814) |
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| Comments |
Selected for resistance to: ChEBI; CHEBI_84050; Trabectedin (Ecteinascidin-743; ET-743).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). |
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| Sequence variations |
- Gene fusion; HGNC; HGNC:2726; DDIT3 + HGNC; HGNC:4010; FUS; Name(s)=FUS-DDIT3, TLS-CHOP (from parent cell line).
- Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
|
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| Disease |
Myxoid liposarcoma (NCIt: C27781)
Myxoid/round cell liposarcoma (ORDO: Orphanet_99967) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_S813 (402-91) |
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| Sex of cell |
Male |
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| Category |
Transformed cell line |
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| Publications | PubMed=21805478; DOI=10.1002/ijc.26340
Sarah Uboldi, Sergio Bernasconi, Michela Romano, Sergio Marchini, Ilaria Fuso Nerini, Giovanna Damia, Monica Ganzinelli, Elena Marangon, Federica Sala, Luca Clivio, Giovanna Chiorino ...Show all 24 authors... , Silvana Di Giandomenico, Mariano Rocchi, Oronzo Capozzi, Geoffrey Paul Margison, Amanda Jean Watson, Anna Maria Caccuri, Anna Pastore, Andrea Fossati, Roberto Mantovani, Federica Grosso, Juan C. Tercero, Eugenio Erba, Maurizio D'Incalci; Show fewer authors
Characterization of a new trabectedin-resistant myxoid liposarcoma cell line that shows collateral sensitivity to methylating agents.
Int. J. Cancer 131:59-69(2012) |
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| Cross-references |
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| Encyclopedic resources |
Wikidata; Q54602863
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| Entry history |
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| Entry creation | 03-Feb-2014 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 11 |
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