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Cellosaurus ONS-F8 (CVCL_S736)

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Cell line name ONS-F8
Accession CVCL_S736
Resource Identification Initiative To cite this cell line use: ONS-F8 (RRID:CVCL_S736)
Comments Population: Japanese.
Selected for resistance to: NCIt; C129643; Cesium-137 gamma radiation.
Transformant: NCIt; C129643; Cesium-137 gamma radiation.
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Arg (c.182A>G); ClinVar=VCV000013900; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Medulloblastoma, SHH-activated, TP53-wildtype (NCIt: C129443)
Medulloblastoma (ORDO: Orphanet_616)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1624 (ONS-76)
Sex of cell Female
Age at sampling 2Y
Category Cancer cell line
Publications

PubMed=22951319; DOI=10.1093/jrr/rrs078; PMCID=PMC3534279
Lue Sun, Takashi Moritake, Yun-Wen Zheng, Kenshi Suzuki, Ariungerel Gerelchuluun, Zheng-Shan Hong, Junko Zenkoh, Hideki Taniguchi, Koji Tsuboi;
In vitro stemness characterization of radio-resistant clones isolated from a medulloblastoma cell line ONS-76.
J. Radiat. Res. 54:61-69(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_S736
Encyclopedic resources Wikidata; Q54936430
Entry history
Entry creation03-Feb-2014
Last entry update19-Dec-2024
Version number17