Cellosaurus cell line UOK257 (CVCL

Cellosaurus UOK257 (CVCL_S717)

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Cell line name

UOK257

Synonyms

UOK-257; UOK 257

Accession

CVCL_S717

Resource Identification Initiative

To cite this cell line use: UOK257 (RRID:CVCL_S717)

Comments

Omics: Proteomics; PTM; Phosphorylation.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.

Sequence variations

Mutation; HGNC; HGNC:27310; FLCN; Simple; p.His429Profs*27 (c.1285dupC) (1733insC); ClinVar=VCV000003363; Zygosity=Hemizygous (PubMed=18206534).

Disease

Birt-Hogg-Dube syndrome (NCIt: C28244)
Birt-Hogg-Dube syndrome (ORDO: Orphanet_122)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Children:

CVCL_1D69 (UOK257-2)

Sex of cell

Male

Age at sampling

46Y

Category

Cancer cell line

Web pages

Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/u/cell-lines-detail-605.html

Publications

PubMed=17028174; DOI=10.1073/pnas.0603781103; PMCID=PMC1592464
Masaya Baba, Seung-Beom Hong, Nirmala Sharma, Michelle B. Warren, Michael L. Nickerson, Akihiro Iwamatsu, Dominic Esposito, William K. Gillette, Ralph F. Hopkins 3rd, James L. Hartley, Mutsuo Furihata ...Show all 17 authors... , Shinya Oishi, Wei Zhen, Terrence R. Burke Jr., William Marston Linehan, Laura S. Schmidt, Berton Zbar; Show fewer authors
Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling.
Proc. Natl. Acad. Sci. U.S.A. 103:15552-15557(2006)

PubMed=18206534; DOI=10.1016/j.cancergencyto.2007.10.010; PMCID=PMC2440670
You-Feng Yang, Hesed Maria Padilla-Nash, Manish A. Vira, Mones S. Abu-Asab, Daniel Val, Robert A. Worrell, Maria G. Tsokos, Maria J. Merino, Christian P. Pavlovich, Thomas Ried, William Marston Linehan, Cathy D. Vocke;
The UOK 257 cell line: a novel model for studies of the human Birt-Hogg-Dube gene pathway.
Cancer Genet. Cytogenet. 180:100-109(2008)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_S717
SKY/M-FISH/CGH; 5607

Encyclopedic resources

Wikidata; Q54991414

Proteomic databases

PRIDE; PXD030237

Entry history

Entry creation

03-Feb-2014

Last entry update

10-Apr-2025

Version number