ID   UOK257
AC   CVCL_S717
SY   UOK-257; UOK 257
DR   cancercelllines; CVCL_S717
DR   PRIDE; PXD030237
DR   SKY/M-FISH/CGH; 5607
DR   Wikidata; Q54991414
RX   PubMed=17028174;
RX   PubMed=18206534;
WW   Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/u/cell-lines-detail-605.html
CC   Sequence variation: Mutation; HGNC; HGNC:27310; FLCN; Simple; p.His429Profs*27 (c.1285dupC) (1733insC); ClinVar=VCV000003363; Zygosity=Hemizygous (PubMed=18206534).
CC   Omics: Proteomics; PTM; Phosphorylation.
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
DI   NCIt; C28244; Birt-Hogg-Dube syndrome
DI   ORDO; Orphanet_122; Birt-Hogg-Dube syndrome
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   46Y
CA   Cancer cell line
DT   Created: 03-02-14; Last updated: 10-04-25; Version: 15
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RX   PubMed=17028174; DOI=10.1073/pnas.0603781103; PMCID=PMC1592464;
RA   Baba M., Hong S.-B., Sharma N., Warren M.B., Nickerson M.L.,
RA   Iwamatsu A., Esposito D., Gillette W.K., Hopkins R.F. 3rd,
RA   Hartley J.L., Furihata M., Oishi S., Zhen W., Burke T.R. Jr.,
RA   Linehan W.M., Schmidt L.S., Zbar B.;
RT   "Folliculin encoded by the BHD gene interacts with a binding protein,
RT   FNIP1, and AMPK, and is involved in AMPK and mTOR signaling.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15552-15557(2006).
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RX   PubMed=18206534; DOI=10.1016/j.cancergencyto.2007.10.010; PMCID=PMC2440670;
RA   Yang Y.-F., Padilla-Nash H.M., Vira M.A., Abu-Asab M.S., Val D.,
RA   Worrell R.A., Tsokos M.G., Merino M.J., Pavlovich C.P., Ried T.,
RA   Linehan W.M., Vocke C.D.;
RT   "The UOK 257 cell line: a novel model for studies of the human
RT   Birt-Hogg-Dube gene pathway.";
RL   Cancer Genet. Cytogenet. 180:100-109(2008).
//