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Cellosaurus 5-8F/Erbitux (CVCL_S665)

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Cell line name 5-8F/Erbitux
Synonyms 5-8F-Erbitux
Accession CVCL_S665
Resource Identification Initiative To cite this cell line use: 5-8F/Erbitux (RRID:CVCL_S665)
Comments Problematic cell line: Contaminated. Parent cell line (5-8F) has been shown to be an hybrid of HeLa and a cell line of unknown origin.
Doubling time: 142.30 hours (PubMed=21122407).
Selected for resistance to: DrugBank; DB00002; Cetuximab (Erbitux).
Sequence variations
  • Gene fusion; HGNC; HGNC:1490; CAPZA2 + HGNC; HGNC:7029; MET; Name(s)=CAPZA2-MET (from parent cell line).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C528 (5-8F)
Category Hybrid cell line
Publications

PubMed=21122407; DOI=10.3760/cma.j.issn.0253-3766.2010.08.004
Qiang Zuo, Rong-Cheng Luo;
Relationship between the insulin-like growth factor 1 receptor signaling pathway and the resistance of nasopharyngeal carcinoma to cetuximab.
Zhonghua Zhong Liu Za Zhi 32:575-579(2010)

Cross-references
Encyclopedic resources Wikidata; Q54603664
Polymorphism and mutation databases Cosmic; 1459416
Entry history
Entry creation03-Feb-2014
Last entry update27-Nov-2025
Version number16