• Gene fusion; HGNC; HGNC:13222; BCL11B + HGNC; HGNC:2488; NKX2-5; Name(s)=NKX2.5-BCL11B (from parent cell line).
  
• Mutation; HGNC; HGNC:16712; FBXW7; Simple; p.Arg465Cys (c.1393C>T); ClinVar=VCV000376414; Zygosity=Heterozygous (from parent cell line).
  
• Mutation; HGNC; HGNC:3765; FLT3; Simple; p.Ala627Thr (c.1879G>A); Zygosity=Heterozygous (from parent cell line).
  
• Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
  
• Mutation; HGNC; HGNC:7881; NOTCH1; Simple; p.Leu1593_Arg1594insProArgLeuProHisAsnSerSerPheHisPheLeu (c.4780_4781ins36); Zygosity=Heterozygous (from parent cell line).
  
• Mutation; HGNC; HGNC:7881; NOTCH1; Simple; p.Pro2412Thr (c.7234C>A); Zygosity=Heterozygous (from parent cell line).
  
• Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Heterozygous (from parent cell line).
  
• Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Heterozygous (from parent cell line).
  

PubMed=6929188; DOI=10.1016/0006-2952(80)90391-3
Andre Rosowsky, Herbert Lazarus, Grace C. Yuan, William R. Beltz, Lynn Mangini, Herbert T. Abelson, Edward J. Modest, Emil Frei 3rd;
Effects of methotrexate esters and other lipophilic antifolates on methotrexate-resistant human leukemic lymphoblasts.
Biochem. Pharmacol. 29:648-652(1980)

CLPUB00028
Enrico Mini, William Douglas Medina, Srinivasan Srimatkandada, Barbara A. Moroson, Joseph Rocco Bertino;
Establishment and characterization of methotrexate-resistant human cell lines and effects of folate antagonists.
Clin. Res. 31:509A-509A(1983)

PubMed=3855284
Enrico Mini, Barbara A. Moroson, Christine T. Franco, Joseph Rocco Bertino;
Cytotoxic effects of folate antagonists against methotrexate-resistant human leukemic lymphoblast CCRF-CEM cell lines.
Cancer Res. 45:325-330(1985)