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Cellosaurus EpH4 1424 (CVCL_S643)

[Text version]
Cell line name EpH4 1424
Accession CVCL_S643
Resource Identification Initiative To cite this cell line use: EpH4 1424 (RRID:CVCL_S643)
Comments Genetic integration: Method=Transfection; Gene=MGI; MGI:1346866; Map2k1 (Note=With p.Ser218Asp and p.Ser222Asp = MEKDD, constitutively activated form).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
Cell type: Epithelial cell of mammary gland; CL=CL_0002327.
Disease Malignant neoplasms of the mouse mammary gland (NCIt: C21678)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/c.
Hierarchy Parent: CVCL_S646 (EpH4 betaMEKDD-116)
Children:
CVCL_S644 (EpH4 1424.1)CVCL_S645 (EpH4 1424.2)
Sex of cell Female
Age at sampling Adult
Category Cancer cell line
Publications

PubMed=12183438
Pinkas J., Leder P.
MEK1 signaling mediates transformation and metastasis of EpH4 mammary epithelial cells independent of an epithelial to mesenchymal transition.
Cancer Res. 62:4781-4790(2002)

Cross-references
Cell line collections (Providers) ATCC; CRL-3071
Encyclopedic resources Wikidata; Q54832371
Entry history
Entry creation03-Feb-2014
Last entry update19-Dec-2024
Version number13